Rufinamide

  • P. N. Patsalos
Chapter

Abstract

Rufinamide (Fig. 1) corresponds chemically to 1-[(2,6-difluorophenyl) methyl]-1-hydro-1,23-triazole-4carboxamide with an empirical formula of C10H8F2N4O and a molecular weight of 238.19.

Keywords

Lamotrigine Topiramate Pregabalin Levetiracetam Vigabatrin 

References

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    Brodie MJ, Rosenfeld WE, Vazquez B, et al. Rufinamide for the adjunctive treatment of partial seizures in adults and adolescents a randomized placebo-controlled trial. Epilepsia. 2009;50:1899–909.PubMedCrossRefGoogle Scholar
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    May TW, Boor R, Rambeck B, Jurgens U, Korn-Merker E, Brandt C. Serum concentrations of rufinamide in children and adults with epilepsy the influence of dose, age, and comedication. Ther Drug Monit. 2011;33:214–21.PubMedGoogle Scholar

Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  • P. N. Patsalos
    • 1
    • 2
  1. 1.UCL-Institute of Neurology Department of Clinical and Experimental EpilepsyLondonLondon
  2. 2.Epilepsy Society Chalfont Centre for EpilepsyBuckinghamshireUK

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