Cytopathology pp 423-451 | Cite as

Soft Tissue and Bone and Joint Cytology

  • Michael T. Sheaff
  • Naveena Singh


Cytology is often used as a first stage in the diagnosis of any superficial mass, although core biopsy or excision biopsy may be more appropriate depending on the clinical scenario. Aspiration cytology is straight forward in most cases, and it can be extremely useful for the initial assessment of a range of soft tissue tumors. Although cytology is mainly used for the diagnosis of soft tissue tumors in specialist centers, it is appropriate for any general cytologist to have a reasonable knowledge of the typical findings of any soft tissue lesion as these can be found in deep locations, often within organs, and their nature is not immediately apparent to the aspirator. This chapter outlines the diagnostic features of the cytological appearance of soft tissue and bone tumors, and it also describes the microscopic appearance that helps diagnose a range of joint diseases.


Soft Tissue Tumor Malignant Peripheral Nerve Sheath Tumor Soft Tissue Lesion Granular Cell Tumor Epithelioid Sarcoma 
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Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  • Michael T. Sheaff
    • 1
  • Naveena Singh
    • 1
  1. 1.Department of Cellular PathologyBarts Health NHS TrustLondonUK

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