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Dementia in Clinical Practice: A Neurological Perspective

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Abstract

The investigation of cases of suspected dementia has perhaps gained a higher profile in recent years. This may reflect a combination of the increasing availability of more sophisticated investigation methods and the search for disease biomarkers which might be used as surrogates for pathological confirmation of disease. For example, recent diagnostic criteria for Alzheimer’s disease (AD; Dubois et al. 2007; Box 4.1; McKhann et al. 2011) enshrine investigation findings which examine potential AD biomarkers. Nevertheless, at time of writing dementia remains a clinical diagnosis. Diagnostic errors based on overreliance on investigations, particularly structural imaging reported to show brain atrophy, have been encountered (Davies and Larner 2009; Larner 2004a).

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  1. Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Liverpool, UK

    Dr. A. J. Larner (Consultant Neurologist)

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  1. Dr. A. J. Larner
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© 2012 Springer-Verlag London Limited

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Larner, A.J. (2012). Investigation. In: Dementia in Clinical Practice: A Neurological Perspective. Springer, London. https://doi.org/10.1007/978-1-4471-2377-4_4

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  • DOI: https://doi.org/10.1007/978-1-4471-2377-4_4

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