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Rash and Hypotension During Transfusion

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Transfusion Medicine

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Abstract

A 16-year-old female with suspected autoimmune liver disease requires liver biopsy. Her platelet count is 38 × 109/L. On the day of planned intervention, she is transfused a unit of platelets. Ten minutes into the transfusion, she became short of breath and wheezy, developed a widespread rash and abdominal pain, and became hypotensive (BP 96/48 mmHg). Transfusion was stopped, with about one-half of the bag content transfused. She had no previous history of allergic reactions or blood transfusion.

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References

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Further Reading

  • Cooper MD, Schroeder HW. Primary immune deficiency diseases. In: Fauci A, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, Loscalzo J, editors. Harrison’s principles of internal medicine. 17th ed. New York: Mc Graw-Hill; 2008. p. 2053–60.

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  • Sandler SG. How I manage patients suspected of having had an IgA anaphylactic transfusion reaction. Transfusion. 2006;46:10–3.

    Article  PubMed  Google Scholar 

  • Wu C, Heddle NM. Febrile and allergic transfusion reactions. In: Murphy MF, Pamphilon DH, editors. Practical transfusion medicine. 3rd ed. Oxford: Blackwell; 2009. p. 83–9.

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Authors and Affiliations

  1. Kings College Hospital Haematology, Denmark Hill, SE5 9RS, London, UK

    Dr. Aleksandar Mijovic

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  1. Dr. Aleksandar Mijovic
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© 2012 Springer-Verlag London Limited

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Mijovic, A. (2012). Rash and Hypotension During Transfusion. In: Transfusion Medicine. Springer, London. https://doi.org/10.1007/978-1-4471-2182-4_9

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  • DOI: https://doi.org/10.1007/978-1-4471-2182-4_9

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-2181-7

  • Online ISBN: 978-1-4471-2182-4

  • eBook Packages: MedicineMedicine (R0)

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