Anaplastic Thyroid Cancer
Anaplastic, or undifferentiated, thyroid cancer is one of the most aggressive solid tumors with an extremely poor prognosis. It is believed that around 50 % of anaplastic thyroid cancers arise from a prior or coexistent differentiated thyroid carcinoma. The loss of the tumor suppressor gene p53 is an important step in this process.
KeywordsThyroid Cancer Thyroid Carcinoma Clinical Target Volume Local Control Rate Medullary Thyroid Cancer
- ZYBRESTAT(TM) (CA4P) improves overall survival in a phase 2/3 trial (FACT Study) of patients with Anaplastic Thyroid Cancer (ATC). OXiGENE press release of Phase 2/3 results Sept 2010 posted at http://www.globenewswire.com/newsroom/news.html?d=201261.