Medullary Thyroid Cancer

  • Barney HarrisonEmail author
  • Bruno Carnaille


Medullary thyroid cancer is rare, in 25 % of cases genetically determined (multiple endocrine neoplasia type 2), and should be treated by a specialized multidisciplinary team in the Cancer Center. In most cases, total thyroidectomy and at least central compartment lymph node dissection are required. Serum calcitonin levels prior to and after operation indicate the extent of disease and the prognosis. Targeted biological therapy with a multistep tyrosine kinase inhibitor is a new option for patients with advanced disease.


Total Thyroidectomy Multiple Endocrine Neoplasia Medullary Thyroid Cancer Calcitonin Level Serum Calcitonin Level 
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Further Reading

  1. Kloos RT, Eng C, Evans DB, Francis GL, Gagel RF, Gharib H, et al. Medullary thyroid cancer: management guidelines of the American thyroid association. Thyroid. 2009;19(6):565–612.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag London 2014

Authors and Affiliations

  1. 1.Department of Endocrine SurgeryRoyal Hallamshire HospitalSheffieldUK
  2. 2.Department of Endocrine SurgeryUniversity Hospital, Hopital HuriezLilleFrance

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