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Tumors of Fibrous Tissue Origin

  • Claus-Peter Adler
  • Kazimierz Kozlowski

Abstract

Among all primary bone tumors nonossifying fibroma is the most frequently occurring one in children and adolescents. It is questionable whether it is a true neoplasm because it usually undergoes a spontaneous resolution later in life. The lesion is fibrous and appears as an osteolytic,cystic defect in the metaphysis of a bone and is well delimited by a grape-like marginal sclerosis consisting of fibrous tissue in a whorled pattern and including histiocytes,foam cells and multinucleated giant cells. No bone formation is seen within the lesion. It develops eccentrically in a bone and, in contrast to metaphyseal fibrous cortical defect, expands towards the cortex from the inside which will be rarefied. Many nonossifying bone fibromas are detected accidentally, i.e. they are symptomless. Multiple lesions simultaneously in different bones do occur.

Keywords

Fibrous Dysplasia Multinucleated Giant Cell Malignant Fibrous Histiocytoma Giant Cell Tumor Fibrous Histiocytoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag London Limited 1993

Authors and Affiliations

  • Claus-Peter Adler
    • 1
  • Kazimierz Kozlowski
    • 2
  1. 1.Reference Center of Bone Disease, Institute of PathologyUniversity of FreiburgFreiburg i. Br.Germany
  2. 2.Department of RadiologyThe Children’s HospitalCamperdown, SydneyAustralia

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