Abstract
Reparative giant cell granuloma of the jaw bones is another reactive lesion seen in children and adolescents; it may appear to be a “bone cyst” or may have a destructive area that gives the impression of being a malignant growth. It is a nontumorous lesion, occurring in the jaw bones, that consists of a granulation tissue rich in osteoclastic giant cells and is a reactive organization tissue following traumatic bone damage. An osteoclastoma or “brown tumor” in hyperparathyroidism must be excluded in diagnosis, but most giant cell lesions in the jaws are reparative giant cell granulomas. A simple curettage is the adequate therapy, and complete healing can be expected.
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Literature
Adler CP. Knochenzysten. Beitr Pathol Anat 1973; 150: 103–31
Adler CP. Teleangiectatic osteosarcoma of the femur with features of an aggressive aneurysmal bone cyst. Skeletal Radiol 1980; 5: 56–60
Adler CP. Klassifikation der Knochentumoren und Pathologie der gutartigen und semimalignen Knochentumoren. Klinisch-radiologisches Seminar, Bd X. Stuttgart: Thieme, 1980
Adler CP. Granulomatöse Erkrankungen im Knochen. Verh Dtsch Ges Pathol 1980; 64: 359–65
Adler CP, Härle F. Zur Differentialdiagnose osteofibröser Kiefererkrankungen. Verh Dtsch Ges Pathol 1974; 58: 308–14
Adler CP. Recidivierende cortikale diaphysäre aneurysmatische Knochenzyste der Tibia. Verh Dtsch Ges Pathol 1974; 58: 256–8
Adler CP, Schmidt A. Aneurysmale Knochenzyste des Femurs mit malignem Verlauf. Verh Dtsch Ges Pathol 1978; 62: 487
Adler CP, Uehlinger E. Grenzfälle bei Knochentumoren. Präneoplastische Veränderungen und Geschwülste fraglicher Dignität. Verh Dtsch Ges Pathol 1979; 63: 352–8
Austin LT Jr, Dahlin DC, Royer EQ. Giant-cell reparative granuloma and related conditions affecting the jawbones. Oral Surg 1959; 12: 1285–95
Baker DM. Benign unicameral bone cyst: a study of forty-five cases with long-term follow-up. Clin Orthop 1970; 71: 140–51
Biesecker JI, Marcove RC, Huvos AG, Mike V. Aneurysmal bone cysts: a clinicopathologic study of 66 cases. Cancer (Phil) 1970; 26: 615–25
Bonk U. Zur Problematik der Riesenzelltumoren und Riesenzellgranulome im Kieferknochen. In: Schuchardt K, Pfeifer G. Grundlagen, Entwicklung und Fortschritte der Mund-, Kiefer-und Gesichtschirurgie, Bd. XXI. Stuttgart: Thieme, 1976: 161–4
Boseker EH, Bickel WH, Dahlin DC. A clinicopathologic study of simple unicameral bone cysts: Surg Gynecol Obstet 1968; 127: 550–60
Campbell CJ, Papademetrious T, Bonfiglio M. Melorheostosis: a report of the clinical, roentgenographic and pathological findings in fourteen cases. J Bone Jt Surg 1968;A-50:1281–304
Clough JR, Price CHG. Aneurysmal bone cysts. J Bone Jt Surg 1968;B-50:116–27
Cohen J. Simple bone cysts. Studies of cyst fluid in six cases with a theory of pathogenesis. J Bone Jt Surg 1960; A-42:609–16
Connolly J, Secor M. Cortisone treatment of pathologic fracture through a bone.cyst. Nebr Med J 1982; 67: 286–7
Crane AR, Scarano JJ. Synovial cysts (ganglia) of bone. Report of two cases. J Bone Jt Surg 1967;A-49:355–61
Dabska M, Buraczewski J. Aneurysmal bone cyst: pathology, clinical course and radiologic appearance. Cancer (Phil) 1969; 23: 371–89
Fahey J, O’Brien E. Subtotal resection and grafting in selected cases of solitary unicameral bone cysts. J Bone Jt Surg 1973;A-55:59–68
Gold RH, Mirra JM. Melorheostosis. Skeletal Radiol 1977; 2: 57–8
Green A, Ellswood WH, Collins JR. Melorheostosis and osteopoikiosis — with a review of the literature. Am J Roentgenol 1962; 87: 1096–111
Hove E, Sury B. Melorheostosis: Report on five cases with follow-up. Acta Orthop Scand 1971; 42: 315–19
Hughston JC, Whatley GS, Stone MM. Myositis ossificans traumatica (myo-osteosis). Sth Med J (Bgham, Ala) 1962; 55: 1167–70
Jaffe HL. Giant-cell reparative granuloma, traumatic bone cyst, and fibrous (fibro-osseous) dysplasia of the jawbones. Oral Surg 1953; 6: 159–75
Lagier R, Cox JN. Pseudomalignant myositis ossificans. A pathological study of eight cases. Hum Pathol 1975; 6: 653–65
Lodwick GS. Juvenile unicameral bone cyst. A roentgen reappraisal. Am J Roentgenol 1958; 80: 495–504
Martin SJ, Schiller JE. Unicameral bone cyst of the second metatarsal with pathologic fracture. J Am Pediatr Med Assoc 1987; 77: 143–7
Neer CS, Francis KC, Marcove RC, Terz J, Carbonara PN. Treatment of unicameral bone cyst. A follow-up study of one hundred seventy-five cases. J Bone Jt Surg 1966; A-48:731–45
Norman A, Schiffman M. Simple bone cyst: factors of age dependency. Radiology 1977; 124: 779–82
Oppenheim WL, Galleno H. Operative treatment versus steroid injection in the management of unicameral bone cysts. J Pediatr Orthop 1984; 4: 1–7
Reynolds J. The “fallen fragment sign” in the diagnosis of unicameral bone cysts. Radiology 1969; 92: 949–53
Robins PR, Peterson HA. Management of pathologic fractures through unicameral bone cysts. JAMA 1972; 222: 80–1
Sanerkin NG, Mott MG, Roylance J. An unusual intra-osseous lesion with fibroblastic, osteoclastic, osteoblastic, aneurysmal and fibromyxoid elements. “Solid” variant of aneurysmal bone cyst. Cancer 1983; 51: 2278–86
Savastana AA. The treatment of bone cysts with intracyst injection of steroids. Rhode Island Med J 1979; 62: 93–5
Schulz A, Märker R, Delling G. Central giant cell granuloma. Histochemical and ultrastructural study on giant cell function. Virchows Arch [A] 1976; 371: 161–70
Skajaa T. Myositis ossificans. Acta Chir Scand 1958; 116: 68–72
Spence KF, Bright RW, Fitzgerald SP. Solitary unicameral bone cysts: Treatment with freeze-dried crushed cortical bone allograft. J Bone Jt Surg 1976;A-58:636–41
Tillmann B, Dahlin DC, Lipscomb PR, Stewart JR. Aneurysmal bone cyst — an analysis of ninety-five cases. Mayo Clin Proc 1968; 43: 478–95
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© 1993 Springer-Verlag London Limited
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Adler, CP., Kozlowski, K. (1993). Reparative Giant Cell Granuloma of the Jaw Bones. In: Primary Bone Tumors and Tumorous Conditions in Children. Springer, London. https://doi.org/10.1007/978-1-4471-1951-7_14
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DOI: https://doi.org/10.1007/978-1-4471-1951-7_14
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