Epidemiology of Malignant Melanoma
The melanomas occur at a variety of anatomical sites, different phenotypes and genotypes strongly influence their incidence, and they have recognizable precursor lesions. All of this Variation presents opportunities for fruitful comparisons. As a result, in a high risk population known factors can account for perhaps half the cases (English and Armstrong 1988). This is about the same as the proportion for female breast cancer (Bruzzi et al. 1985). Yet the epidemiology of melanoma is loaded with paradox. Generalizations, if they can be offered at all, are hedged with exceptions. New data, for example the finding that in a high risk population, small melanomas were not associated with the usual host factors (Schneider et al. 1987), often do not fit in.
KeywordsDioxide Europe Ozone Catalysis Chlorine
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- Evans RD, Kopf AW, Lew RA et al. (1988) Risk factors for the development of malignant melanoma- 1: Review of case-control studies. Dermatol Surg Oncol 14: 393–408Google Scholar
- Lee JAH (1991) Trends in melanoma incidence and mortality. Clin Dermatol (in press)Google Scholar
- Longstreth JD (1987) Ultraviolet radiation and melanoma. With a special focus on assessing the risks of stratospheric ozone depletion. US Environmental Protection Agency, Washington, DCGoogle Scholar
- Muir CS, Nectoux J (1982) Time trends: malignant melanoma of the skin. In: Magnus K (ed.) Trends in cancer incidence. Hemisphere Publishing Corporation, Washington, pp 365–385Google Scholar
- Osterlind A. (1987) Trends in incidence of ocular malignant melanoma in Denmark, 1943–1982 Int J Cancer 40: 161–164Google Scholar
- Osterlind A, Tucker MA, Stone BJ. (1988a) The Danish case-control control study of cutaneous malignant melanoma. II. Importance of UV-light exposure. Int J Cancer 42: 319–324Google Scholar
- Osterlind A, Hou-Jensen K, Jensen OM (1988b) Incidence of cutaneous malignant melanoma in Denmark, 1978–1982. Atomic site distribution, histologic types, and comparisons with nonmelanoma skin cancer. Br J Cancer 58: 385–391Google Scholar
- Reilly WK, Administrator, US Environmental Protection Agency (1991) Text of Public Statement: AprilGoogle Scholar
- Schneider JS, Sagebiel RW, Moore II DH, Lawton GM (1987) Melanoma surveillance and earlier diagnosis. Lancet i: 1435Google Scholar