High-Density Lipoprotein Cholesterol, Triglycerides and Coronary Heart Disease
High-density lipoprotein (HDL) cholesterol, plasma levels of the triglyceride (TG)-rich lipoproteins and the risk of coronary heart disease (CHD) are interrelated. There exists a strong negative association between levels of HDL cholesterol and CHD risk, a weaker positive relation between TGs and CHD risk, and a strong inverse association between plasma levels of HDL and of the TG-rich lipoproteins. When HDL cholesterol TGs and CHD risk are considered together, the status of each in the triad becomes less clear.
KeywordsCholesterol Obesity Lipase Assimilation Adenine
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- Chung BH, Segrest JP, Smith K, Griffin FM, Brouillette CG (1989) Lipolytic surface remnants of triglyceride-rich lipoproteins are cytotoxic to macrophages but not in the presence of high density lipoprotein: a possible mechanism of atherogenesis? J Clin Invest 83:1363–1374PubMedCrossRefGoogle Scholar
- Eckel RH, Yost TJ (1989) HDL subfractions and adipose tissue metabolism in the reduced-obese state. Am J Physiol 256:E740–740E746Google Scholar
- Miesenböck G, Patsch JR (1990) Relationship of triglyceride and high-density lipoprotein metabolism. Atherosclerosis Rev 18:119–128Google Scholar