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Ideal Immunosuppression After Renal Transplantation: Are Steroids Needed?

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International Yearbook of Nephrology 1992

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Abstract

Prior to the introduction of cyclosporin in the early 1980’s, it was widely held that steroids were a necessary part of immunosuppression for successful renal transplantation. The concept of using a “low dose” prednisolone approach, reported by McGeown in 1977 (1) was slow to be accepted until controlled trial evidence was forthcoming (2). Attempts to withdraw prednisolone from long term maintenance regimes even in stable, carefully selected patients (on azathioprine) were accompanied by frequent irreversible rejection episodes (3).

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Author information

Authors and Affiliations

  1. Renal Unit, The Queen Elizabeth Hospital, Woodville, South Australia, Australia

    Timothy H. Mathew

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  1. Timothy H. Mathew
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Editors and Affiliations

  1. Department of Nephrology, University of Naples, Naples, Italy

    Vittorio E. Andreucci

  2. Middlesex School of Medicine The Rayne Institute, University College, London, UK

    Leon G. Fine

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© 1991 Springer-Verlag London Limited

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Mathew, T.H. (1991). Ideal Immunosuppression After Renal Transplantation: Are Steroids Needed?. In: Andreucci, V.E., Fine, L.G. (eds) International Yearbook of Nephrology 1992. Springer, London. https://doi.org/10.1007/978-1-4471-1892-3_14

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  • DOI: https://doi.org/10.1007/978-1-4471-1892-3_14

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1894-7

  • Online ISBN: 978-1-4471-1892-3

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