Advertisement

Bone: The Architecture of Bone and How it is Influenced by External Loading

  • L. E. Lanyon

Abstract

Everyone will agree that one of the principal influences on whether a prosthetic fixation succeeds or not is the situation at the interface. The interface will react in many ways according to its specific characteristics. However, the interface is also the perimeter of the bone architecture whose position is determined by another set of influences which result from its role as a bearer of functional loads. The data presented relate to the functional determinants of bone architecture.

Keywords

Bone Cement Bone Architecture Optical Path Difference Implant Bone Interface Osteogenic Response 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References and Further Reading

  1. Ferris BD, Klenerman L, Dodds RA, Bitensky L, Chayen J (1987) Altered organisation of non-collagenous bone matrix in osteoporosis. Bone 8:285–288PubMedCrossRefGoogle Scholar
  2. Jaworski ZFG, Uhthoff HK (1986) Reversibility of non traumatic disuse osteoporosis during its active phase. Bone 7:431–439PubMedCrossRefGoogle Scholar
  3. Lanyon LE (1987) Functional strain in bone tissue as an objective, and controlling stimulus for adaptive bone remodelling. J Biomech 20:1083–1093PubMedCrossRefGoogle Scholar
  4. Lanyon LE, Bourn S (1979) The influence of mechanical function on the development and remodelling of the tibia. J Bone Joint Surg (Am) 61:263–273Google Scholar
  5. Lanyon LE, Rubin CT (1984) Static versus dynamic loads as an influence on bone remodelling. J Biomech 17:892–905CrossRefGoogle Scholar
  6. Lanyon LE, Smith RN (1970) Bone strain in the tibia during normal quadrupedal locomotion. Acta Orthop Scand 41:238–248PubMedCrossRefGoogle Scholar
  7. Lanyon LE, Hampson WEJ, Goodship AE, Shah JS (1973) Bone deformation recorded in vivo from strain gauges attached to the human tibial shaft. Acta Orthop Scand 46:256–268Google Scholar
  8. Lanyon LE, Paul IL, Rubin CT, Thrasher EL, DeLaura R, Rose RM, Radin EL (1981) In vivo strain measurements from bone and prosthesis following total hip replacement. An experimental study in sheep. J Bone Joint Surg (Am) 63:989–1000Google Scholar
  9. Pead MJ, Skerry TM, Lanyon LE (1988a) Direct transformation from quiescence to bone formation in the adult periosteum following a single brief period of bone loading. J Bone Min Res 3:647–656CrossRefGoogle Scholar
  10. Pead MJ, Suswillo R, Skerry TM, Vedi S: Lanyon LE (1988b) Increased 3H-uridine levels in osteocytes following a single short period of dynamic bone loading in vivo. Calcif Tissue Int 43:92–96PubMedCrossRefGoogle Scholar
  11. Rodriguez JL Palacios J, Garcia-Alix A, Pastor I, Paniagua R (1988) Effects of immobilisation on foetal bone development. A morphometric study in newborns with congenital neuro muscular diseases with intra-uterine onset. Calcif Tissue Int 43:335–339PubMedCrossRefGoogle Scholar
  12. Rubin CT, Lanyon LE (1984) Regulation of bone formation by applied dynamic loads. J Bone Joint Surg (Am) 66:397–402Google Scholar
  13. Rubin CT, Lanyon LE (1985) Regulation of bone mass by mechanical strain magnitude. Calcif Tissue Int 37:411–417PubMedCrossRefGoogle Scholar
  14. Simkin A, Ayalon J, Leichter I (1987) Increased trabecular bone density due to bone loading exercises in postmenopausal osteoporotic women. Calcif Tissue Int 40:59–63PubMedCrossRefGoogle Scholar
  15. Skerry TM, Bitensky L, Chayen J, Lanyon LE (1988) Loading-related reorientation of bone proteoglycan in vivo. Strain memory in bone tissue? J Orthop Res 6:547–551PubMedCrossRefGoogle Scholar
  16. Skerry TM, Bitensky L, Chayen J, Lanyon LE (1989) Early strain related changes in enzyme activity in osteocytes following bone loading in vivo. J Bone Min Res 4:783–788CrossRefGoogle Scholar
  17. Skerry TM, Suswillo R, El Haj AJ, Ali NN, Dodils RA, Lanyon LE (1990) Load induced proteoglycan orientation in bone tissue in vivo and in vitro. Calcif Tissue Int (in press)Google Scholar
  18. Uhthoff HK, Jaworski ZFG (1978) Bone loss in response to long term immobilisation. J Bone Joint Surg (Br) 60:420–429Google Scholar

Copyright information

© Springer-Verlag London Limited 1990

Authors and Affiliations

  • L. E. Lanyon

There are no affiliations available

Personalised recommendations