Skip to main content

Should HRT be Recommended in the Community?

  • Conference paper
HRT and Osteoporosis
  • 89 Accesses

Abstract

Previous chapters have examined the efficacy and safety of hormone replacement therapy (HRT) and we must now consider whether widespread treatment of our community is appropriate. Because doctors have always been free to offer HRT to women the question for us is not whether an individual doctor should use the drug but whether there should be “national policy” on this matter. Examples of the application of national policies on health include immunisation policy, cervical cancer screening and recently the decision to advise breast cancer screening by mammography. Without adequate resources the application of national policy can be rather fragmented, as has been the case with cervical cancer screening. If there were to be a major expansion of HRT use it would be essential that this would be undertaken in general practice, since there is not a nationwide network of specialist clinics which could undertake the work of advising, treating and monitoring the women and I cannot envisage new resources to set up such a network. If large-scale treatment is to be based in general practice, it would be of great importance to have the willing collaboration of GPs, and their agreement that widespread and reasonably long-term treatment is advisable. Despite the recent growth in the prescription of HRT by GPs, I believe many remain unconvinced that large-scale longer-term treatment is advisable.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Barlow DH, Grosset KA, Hart H, Hart DM. A study of the experience of Glasgow women in the climacteric years. Br J Obstet Gynaecol 1989; 96:1192–7.

    Article  PubMed  CAS  Google Scholar 

  2. Spector T. Use of oestrogen replacement therapy in high risk groups in the United Kingdom. Br Med J 1989; 299:1434–5.

    Article  CAS  Google Scholar 

  3. Ravnikar VA. Compliance with hormone therapy. Am J Obstet Gynecol 1987; 156:1322–4.

    Google Scholar 

  4. Bergvist L, Hans-Olov A, Persson I, Hoover R, Schairer C. The risk of breast cancer after estrogen and estrogen-progestin replacement. N Engl J Med 1989; 321:293–7.

    Article  Google Scholar 

  5. Weiss NR, Ure BL, Ballard JH, Williams AR, Darling DR. Decreased risk of fractures of the hip and lower forearm with postmenopausal use of estrogen. N Engl J Med 1980; 303:1195–8

    Article  PubMed  CAS  Google Scholar 

  6. Kreiger N, Kelsey JL, Holford TR, O’Connell T. An epidemiological study of hip fracture in postmenopausal women. Am J Epidemiol 1982;116:141–8.

    PubMed  CAS  Google Scholar 

  7. Paganini-Hill A, Ross RK, Gerkins VR, Henderson BE, Arthur M, Mack TM. Menopausal estrogen therapy and hip fractures. Ann Intern Med 1981; 95:28–31.

    PubMed  CAS  Google Scholar 

  8. Bush TL, Cowan LD, Barrett-Connor E et al. Estrogen use and all-cause mortality. JAMA 1983; 249:903–6.

    Article  PubMed  CAS  Google Scholar 

  9. Stampfer MJ, Willett WC, Colditz GA, Rosner B, Speizer FE, Hennekens C. A prospective study of postmenopausal estrogen therapy and coronary artery disease. N Eng J Med 1985; 313:1044–9.

    Article  CAS  Google Scholar 

  10. Henderson BE, Paganini-Hill A, Ross RK. Estrogen replacement therapy and protection from acute myocardial infarction. Am J Obstet Gynecol 1988; 159:312–17.

    PubMed  CAS  Google Scholar 

  11. Hunt K, Vessey MP, McPherson K, Coleman M. Long-term surveillance of mortality and cancer incidence in women receiving hormone replacement therapy. Br J Obstet Gynaecol 1987; 94:620–35.

    Article  PubMed  CAS  Google Scholar 

  12. Paganini-Hill A, Ross RK, Henderson BE. Postmenopausal oestrogen treatment and stroke: a prospective study. Br Med J 1988; 297:519–22.

    Article  CAS  Google Scholar 

  13. Persson I, Adami H-O, Bergkvist L, Lindgren A, Pettersson B, Hoover R, Schairer C. Risk of endometrial cancer after treatment with oestrogens alone or in conjunction with progestogens: results of a prospective study. Br Med J 1989; 298:147–51.

    Article  CAS  Google Scholar 

  14. Kaufman DW, Miller DR, Rosenberg L et al. Non-contraceptive estrogen use; the risk of breast cancer. JAMA 1984; 252:63–7.

    Article  PubMed  CAS  Google Scholar 

  15. Brinton LA, Hoover R, Fraumeni JF. Menopausal oestrogens and breast cancer risk: an expanded case-control study. Br J Cancer 1986; 54:825–32.

    Article  PubMed  CAS  Google Scholar 

  16. Wingo PA, Layde PM, Lee NC, Rubin G, Ory HW. The risk of breast cancer in postmenopausal women who have used estrogen replacement therapy. JAMA 1987; 257:209–15.

    Article  PubMed  CAS  Google Scholar 

  17. Ewertz M. Influence of non-contraceptive exogenous and endogenous sex hormones on breast cancer risk in Denmark. Int J Cancer 1988; 42:832–8.

    Article  PubMed  CAS  Google Scholar 

  18. Mills PK, Beeson WL, Phillips RL, Fraser GE. Prospective study of exogenous hormone use and breast cancer risk in Seventh Day Adventists. Cancer 1989; 64:591–7.

    Article  PubMed  CAS  Google Scholar 

  19. Coulter A, MacPherson K, Vessey MP. Do British women undergo too many or too few hysterectomies? Social Sci Med 1988; 27:987–94.

    Article  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1990 Springer-Verlag London Limited

About this paper

Cite this paper

Barlow, D.H. (1990). Should HRT be Recommended in the Community?. In: Drife, J.O., Studd, J.W.W. (eds) HRT and Osteoporosis. Springer, London. https://doi.org/10.1007/978-1-4471-1799-5_27

Download citation

  • DOI: https://doi.org/10.1007/978-1-4471-1799-5_27

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1801-5

  • Online ISBN: 978-1-4471-1799-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics