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Epstein-Barr Virus Infection and Cancer

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The Role of Micro-organisms in Non-infectious Diseases

Part of the book series: Argenteuil Symposia ((ARGENTEUIL))

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Abstract

Evidence linking Epstein-Barr (EB) virus to two human cancers, endemic Burkitt’s lymphoma (BL) [1] and undifferentiated nasopharyngeal carcinoma (NPC) [2], has accumulated steadily over the years [3–5]. Already in 1976 enough was known for it to be evident that EB virus was an essential link in a complicated chain of events leading inexorably to these malignant tumours, and it therefore seemed reasonable to suppose that if infection by the virus could be prevented the incidence of the tumours in populations at risk would be decreased [6]. In view of the compelling analogy afforded by the effect of avoiding cigarette smoking on the incidence of bronchogenic carcinoma [7], it seemed unethical not at least to explore the possibility of vaccine intervention to prevent EB virus infection in the context of BL and NPC.

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Authors
  1. M. A. Epstein
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Editors and Affiliations

  1. Department of Immunohaematology and Blood Bank, University Hospital, 2333 AA, Leiden, The Netherlands

    René R. P. de Vries  & Jon J. van Rood  & 

  2. Department of Cell Biology, The Weizmann Institute of Science, PO Box 26, 76 100, Rehovot, Israel

    Irun R. Cohen

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© 1990 Springer-Verlag London Limited

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Epstein, M.A. (1990). Epstein-Barr Virus Infection and Cancer. In: de Vries, R.R.P., Cohen, I.R., van Rood, J.J. (eds) The Role of Micro-organisms in Non-infectious Diseases. Argenteuil Symposia. Springer, London. https://doi.org/10.1007/978-1-4471-1796-4_8

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  • DOI: https://doi.org/10.1007/978-1-4471-1796-4_8

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1798-8

  • Online ISBN: 978-1-4471-1796-4

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