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Parasitic Disease in Clinical Practice pp 31–47Cite as

‘Opportunistic’ and Other Parasitic Infections in Relation to the Acquired Immune Deficiency Syndrome (AIDS)

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Part of the book series: The Bloomsbury Series in Clinical Science ((BLOOMSBURY))

Abstract

The acquired immune deficiency syndrome (AIDS) is generally considered to be caused by the HIV-1 and HIV-2 retroviruses, despite a minority viewpoint that the close correlation between infection with these agents and the clinical syndrome does not necessarily establish beyond doubt a causative role (Duesberg 1989). The origin of these viruses is the subject of much conjecture (Penny 1988; Sharp and Li 1988; McClure and Schulz 1989; Seale 1989). Although extremely important in ‘Western’ countries, the brunt of the pandemic is being felt in developing ones, especially those in Africa (De Cock et al. 1989; Reeve 1989) where the impact on human population growth and structure over the next few decades is likely to be massive (Anderson et al. 1988). With the prospect of an effective vaccine merely a distant dream (Newmark 1988; Ada 1989), these infections (and their associated diseases) are likely to constitute a dominant theme in health care in a world context for many generations to come.

Patients rarely die of the disease from which they suffer; secondary or terminal infections are the real cause of death. Sir William Osler (1844–1919), St Bartholomew’s Hospital Reports 1916, 52:39

NB Chapters 4 and 9 should be read in conjunction with this one.

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References

  • Ada G (1989) Prospects for a vaccine against HIV. Nature 339: 331–332

    PubMed  CAS  Google Scholar 

  • Aguado JM, Gómez Berne J, Figuera A, Villalobos E de, Fernández-Guerrero ML, Sanchez Fayos J (1983) Visceral leishmaniasis ( Kala-azar) complicating acute leukaemia. J Infect 7: 272–274

    Google Scholar 

  • Allason-Jones E, Mindel A, Sargeaunt P, Williams P (1986) Entamoeba histolytica as a commensal intestinal parasite in homosexual men. N Engl J Med 315: 353–356

    Google Scholar 

  • Alvar J, Verdejo J, Osuna A, Nájera R (1987) Visceral leishmaniasis in a patient seropositive for HIV, Eur J Clin Microbiol 6: 604–606

    PubMed  CAS  Google Scholar 

  • Alvar J, Blazquez J, Najera R (1989) Association of visceral leishmaniasis and human immunodeficiency virus infections. J Infect Dis 160: 560–561

    PubMed  CAS  Google Scholar 

  • Anderson RM, May RM, McLean AR (1988) Possible demographic consequences of AIDS in developing countries. Nature 332: 228–234

    PubMed  CAS  Google Scholar 

  • Antunes F, Carvalho C, Tavares L, Botas J, Forte M, Rio AM del, Dutschmann L, Costa A, Abranches P, Pereira CS, Paiva JED, Araujo FC, Baptista A (1987) Visceral leishmaniasis recrudescence in a patient with AIDS. Trans R Soc Trop Med Hyg 81: 595

    PubMed  CAS  Google Scholar 

  • Badaró R, Carvalho EM, Rocha H, Queiroz AC, Jones TC (1986) Leishmania donovani: an opportunistic microbe associated with progressive disease in three immunocompromised patients. Lancet 1: 647–649

    Google Scholar 

  • Berenguer J, Moreno S, Cercenado E, Bernaldo de Quirós JC, García de la Fuente A, Bouza E (1989) Visceral leishmaniasis in patients infected with human immunodeficiency virus ( HIV ). Ann Intern Med 111: 129–132

    Google Scholar 

  • Bernard E, Rodot S, Michiels JF, Politano S, le Fichoux Y, Dellamonica P (1988) Visceral leishmaniasis in acquired immunodeficiency syndrome. Presse Méd 17: 872

    PubMed  CAS  Google Scholar 

  • Blaser MJ, Cohn DL (1986) Opportunistic infections in patients with AIDS: clues to the epidemiology of AIDS and the relative virulence of pathogens. Rev Infect Dis 8: 21–30

    PubMed  CAS  Google Scholar 

  • Blázquez J, Alvar J, Nájera R (1987) Leishmaniasis in an HIV ( LAV/HTLV III) serologically positive patient. J Infect 14: 89–90

    Google Scholar 

  • Bureau of Hygiene and Tropical Diseases (1985) African AIDS: a bibliography. Bureau of Hygiene and Tropical Diseases, London, pp 1–15

    Google Scholar 

  • Clark IA (1987) Cell-mediated immunity in protection of pathology of malaria. Parasitol Today 3: 300–305

    PubMed  CAS  Google Scholar 

  • Clauvel JP, Couderc LJ, Belmin J, Daniel MT, Rabian C, Seligmann M (1986) Visceral leishmaniasis complicating acquired immunodeficiency syndrome ( AIDS ). Trans R Soc Trop Med Hyg 80: 1010–1011

    Google Scholar 

  • Colebunders R, Lusakumuni K, Nelson AM, Gigase P, Lebughe I, Marek E van, Kapita B, Francis H, Salaun J-J, Quinn TC, Piot P (1988) Persistent diarrhoea in Zairian AIDS patients: an endoscopic and histological study. Gut 29: 1687–1691

    PubMed  CAS  Google Scholar 

  • Cook GC (1987a) Opportunistic parasitic infections associated with the acquired immune deficiency syndrome (AIDS); parasitology, clinical presentation, diagnosis and management. Q J Med 65: 967–983

    PubMed  CAS  Google Scholar 

  • Cook GC (1987b) Strongyloides stercoralis hyperinfection syndrome: how often is it missed? Q J Med 64:625–629

    Google Scholar 

  • De Cock KM, Porter A, Odehouri K, Barrere B, Moreau J, Diaby L, Kouadio JC, Heyward WL (1989) Rapid emergence of AIDS in Abidjan, Ivory Coast. Lancet 2: 408–411

    PubMed  Google Scholar 

  • Denis M, Chadee K (1988) Immunopathology of Entamoeba histolytica infections. Parasitol Today 4: 247–252

    PubMed  CAS  Google Scholar 

  • Duesberg PH (1989) Human immunodeficiency virus and acquired immunodeficiency syndrome: correlation but not causation. Proc Natl Acad Sci USA 86: 755–764

    PubMed  CAS  Google Scholar 

  • Eales L-J, Moshtael O, Pinching AJ (1987) Microbicidal activity of monocyte derived macrophages in AIDS and related disorders. Clin Exp Immunol 67: 227–235

    PubMed  CAS  Google Scholar 

  • Edit oral (1989) Aids now a tractable disease? Nature 340: 663

    Google Scholar 

  • Ellakany S, Whiteside TL, Schade RR, Thiel DH van (1987) Analysis of intestinal lymphocyte subpopulations in patients with acquired immunodeficiency syndrome ( AIDS) and AIDS-related complex. Am J Clin Pathol 87: 356–364

    Google Scholar 

  • Elvin KM, Björkman A, Linder E, Heurlin N, Hjerpe A (1988) Pneumocystis carinii pneumonia: detection of parasites in sputum and bronchoalveolar lavage fluid by monoclonal antibodies. Br Med J 297: 381–384

    Google Scholar 

  • Elvin KM, Lumbwe CM, Luo NP, Björkman A, Källenius G, Linder E (1989) Pneumocystis carinii is not a major cause of pneumonia in HIV infected patients in Lusaka, Zambia. Trans R Soc Trop Med Hyg 83: 553–555

    Google Scholar 

  • Ezzell C (1989) Aids closer to becoming a treatable disease. Nature 340: 581

    PubMed  CAS  Google Scholar 

  • Falk S, Helm EB, Hübner K, Stutte HJ (1988) Disseminated visceral leishmaniasis (Kala-azar) in acquired immunodeficiency syndrome ( AIDS ). Pathol Res Pract 183: 253–255

    Google Scholar 

  • Farthing CF, Shanson DC, Gazzard BG (1985) The acquired immune deficiency syndrome: problems associated with the management of Pneumocystis carinii pneumonia. J Infect 11: 103–108

    PubMed  CAS  Google Scholar 

  • Fernández-Guerrero ML, Aguado JM, Buzón L, Barros C, Montalbán C, Martín T, Bouza E (1987) Visceral leishmaniasis in immuncompromised hosts. Am J Med 83: 1098–1102

    PubMed  Google Scholar 

  • Fischl MA, Dickinson GM (1986) Fansidar prophylaxis of Pneumocystis pneumonia in the acquired immunodeficiency syndrome. Ann Intern Med 105: 629

    PubMed  CAS  Google Scholar 

  • Fischl MA, Richman DD, Grieco MH, Gottlieb MS, Volberding PA, Laskin OL, Leedom JM, Groopman JE, Midvan D, Schooley RT, Jackson GG, Durack DT, King D, AZT Collaborative Working Group (1987) The efficacy of azidothymidine ( AZT) in the treatment of patients with AIDS and AIDS-related complex. N Engl J Med 317: 185–191

    Google Scholar 

  • Franco-Vicario R, Beitran de Heredia JM, Rojo P, Hermosa C (1987) Leishmaniasis associated with the acquired immunodeficiency syndrome. Med Clin (Bare) 88: 565–566

    CAS  Google Scholar 

  • Fuzibet JG, Marty P, Taillan B, Bertrand F, Pras P, Pesce A, LeFichoux Y, Dujarin P (1988) Is Leishmania infantum an opportunistic parasite in patients with anti-human immunodeficiency virus antibodies? Arch Intern Med 148: 1228

    PubMed  CAS  Google Scholar 

  • Gelb A, Miller S (1986) AIDS and gastroenterology. Am J Gastroenterology 81: 619–622

    CAS  Google Scholar 

  • Genta RM (1989) Immunology. In: Grove DI (ed) Strongyloidiasis: a major roundworm infection of man. Taylor and Francis, London, pp 133–153

    Google Scholar 

  • Girard P-M, Lepretre A, Detruchis P, Matheron S, Coulaud J-P (1989a) Failure of pyrimethamine-clindamycin combination for prophylaxis of Pneumocystis carinii pneumonia. Lancet 1: 1459

    PubMed  CAS  Google Scholar 

  • Girard P-M, Landman R, Gaudebout C, Lepretre A, Lottin P, Michon C, Truchis P de, Matheron S, Camus F, Farinotti R, Marche C, Coulaud J-P, Saimot AG (1989b) Prevention of Pneumocystis carinii pneumonia relapse by pentamidine aerosol in zidovudine-treated AIDS patients. Lancet 1: 1348–1353

    PubMed  CAS  Google Scholar 

  • Golden JA, Chernoff D, Hollander H, Feigal D, Conté JE (1989) Prevention of Pneumocystis carinii pneumonia by inhaled pentamidine. Lancet 1: 654–657

    PubMed  CAS  Google Scholar 

  • Gonzales FM, Lorenzo AA, Perez JL (1986) Visceral leishmaniasis that proved fatal associated with HTLV-III infection. Med Clin (Bare) 87: 730–731

    Google Scholar 

  • Gonzalez MM, Gould E, Dickinson G, Martinez AJ, Visvesvara G, Cleary TJ, Hensley GT (1986) Acquired immunodeficiency syndrome associated with Acanthamoeba infection and other opportunistic organisms. Arch Pathol Lab Med 110: 749–751

    PubMed  CAS  Google Scholar 

  • Good MF, Miller LH (1989) Involvement of T cells in malaria immunity: implications for vaccine development. Vaccine 7: 3–9

    PubMed  CAS  Google Scholar 

  • Gordin FM, Simon GL, Wofsy CB, Mills J (1984) Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome. Ann Intern Med 100: 495–499

    PubMed  CAS  Google Scholar 

  • Greenberg AE (1989) Studies of the relationship between Plasmodium falciparum malaria and HIV infection in Africa. Vth International Conference on AIDS. Montreal, Canada, Abstract WG07, p 983

    Google Scholar 

  • Grove DI (1989) Clinical manifestations. In: Grove DI (ed) Strongyloidiasis: a major roundworm infection of man. Taylor and Francis, London, pp 155–173

    Google Scholar 

  • Haverkos HW (1984) Assessment of therapy for Pneumocystis carinii pneumonia: PCP therapy project group. Am J Med 76: 501–508

    PubMed  CAS  Google Scholar 

  • Hofmann B, Odum N, Platz P, Ryder LP, Svejgaard A, Nielsen PB, Holten-Andersen W, Gerstoft J, Nielson JO, Mojon M (1985) Humoral responses to Pneumocystis carinii in patients with acquired immunodeficiency syndrome and in immunocompromised homosexual men. J Infect Dis 152: 838–840

    PubMed  CAS  Google Scholar 

  • Hopewell PC (1988) Diagnosis and treatment of Pneumocystis carinii pneumonia. In: Leech JH, Sande MA, Root RK (eds) Parasitic infections. Churchill Livingstone, New York and Edinburgh, pp 195–220

    Google Scholar 

  • Hughes WT (1984) Pneumocystosis. In: Strickland GT (ed) Hunter’s tropical medicine, 6th edn. Saunders, Philadelphia, pp 605–608

    Google Scholar 

  • Hughes WT, Gigliotti F (1988) Nomenclature for Pneumocystis carinii. J Infect Dis 157: 432–433

    PubMed  CAS  Google Scholar 

  • Hughes WT, Smith BL (1984) Efficacy of diaminodiphenylsulfone and other drugs in murine Pneumocystis carinii pneumonitis. Antimicrob Agents Chemother 26: 436–440

    PubMed  CAS  Google Scholar 

  • Kayembe N, Nelson AM, Ilunga N, Angritt P, Kaiengay HM (1989) Pathology of HIV infection in Zaire. Vth International Conference on AIDS. Montreal, Canada, Abstract Th Go 32, p 994

    Google Scholar 

  • Kovacs JA, Masur H (1988) Advances in the biology and immunology of Pneumocystis carinii. In: Leech JH, Sande MA, Root RK (eds) Parasitic infections. Churchill Livingstone, New York and Edinburgh, pp 177–193

    Google Scholar 

  • Kovacs JA, Hiemenz JW, Macher AM, Stover D, Murray HW, Shelhamer J, Lane C, Urmacher C, Honig C, Longo DL, Parker MM, Natanson C, Parrillo JE, Fauci AS, Pizzo PA, Masur H (1984) Pneumocystis carinii pneumonia: a comparison between patients with the acquired immunodeficiency syndrome and patients with other immunodeficiencies. Ann Intern Med 100: 663–671

    Google Scholar 

  • Kovacs JA, Ng VL, Masur H, Leoung G, Hadley WK, Evans G, Lane HC, Ognibene FP, Shelhamer J, Parrillo JE, Gill VJ (1988) Diagnosis of Pneumocystis carinii pneumonia: improved detection in sputum with use of monoclonal antibodies. N Engl J Med 318: 589–593

    PubMed  CAS  Google Scholar 

  • Lancet, (1988) Pneumocystis carinii finds its identity. Lancet 2:522

    Google Scholar 

  • Lane HC, Masur H, Edgar LC, Whalen G, Rook AH, Fauci AS (1983) Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome. N Engl J Med 309: 453–458

    PubMed  CAS  Google Scholar 

  • Leigh TR, Parsons P, Hume C, Husain O AN, Gazzard B, Collins JV (1989) Sputum induction for diagnosis of Pneumocystis carinii pneumonia. Lancet 2: 205 - 207

    PubMed  CAS  Google Scholar 

  • Leoung GS, Mills J, Hopewell PC, Hughes W, Wofsy C (1986) Dapsone-trimethoprim for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. Ann Intern Med 105: 45–48

    PubMed  CAS  Google Scholar 

  • Letona JML de, Vázquez CM, Maestu RP (1986) Visceral leishmaniasis as an opportunistic infection. Lancet 1: 1094

    Google Scholar 

  • Liew FY (1989) Immunity to protozoa. Current Opin Immunol 1: 441–447

    CAS  Google Scholar 

  • Lingenfelser T, Glück T, Scheurlen M, Overkamp D, Jakober B (1989) Pentamidine and hypoglycaemia. Lancet 2: 458

    PubMed  CAS  Google Scholar 

  • Lucas SB (1990) Missing infections in AIDS. Trans R Soc Trop Med Hyg 84 (suppl 1): 34–38

    PubMed  Google Scholar 

  • Lucas S, Sewankambo N, Nambuya A, Nsubuga P, Goodgame R, Mugerwa J, Carswell JW (1988) The morbid anatomy of African AIDS. In: Giraldo G, Beth-Giraldo E, Clumeck N, Gharbi M-R, Kyalwazi SK, The G de (eds) AIDS and associated cancers in Africa. Karger, Basel, pp 124–133

    Google Scholar 

  • Lucas S, Goodgame R, Kocjan G, Serwadda D (1989) Absence of pneumocystosis in Ugandan AIDS patients. AIDS 3: 47–48

    PubMed  Google Scholar 

  • Macfadden WT, Edelson JD, Hyland RH, Rodriguez CH, Inouye T, Rebuck AS (1987) Corticosteroids as adjunctive therapy in treatment of Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome. Lancet 1: 1477–1479

    PubMed  CAS  Google Scholar 

  • Malebranche R, Arnoux E, Guérin JM, Pierre GD, Laroche AC, Péan-Guichard C, Elie R, Morisset PH, Spira T, Mandeville R, Drotman P, Seemayer T, Dupuy J-M (1983) Acquired immunodeficiency syndrome with severe gastrointestinal manifestations in Haiti. Lancet 2: 873 - 878

    PubMed  CAS  Google Scholar 

  • Maayan S, Wormser GP, Widerhorn J, Sy ER, Kim YH, Ernst JA (1987) Strongyloides stercoralis hyperinfection in a patient with the acquired immune deficiency syndrome. Am J Med 83: 945–948

    Google Scholar 

  • McClure MO, Schulz TF (1989) Origin of HIV. Br Med J 298: 1267–1268

    CAS  Google Scholar 

  • McLeod D, Neill P, Robertson VJ, Latif AS, Emmanuel J, Els JE, Gwanzura LKZ, Trijssenaar FEJ, Nziramasanga P, Jongeling GR, Katzenstein DA, Nkanza N, Lucas SB (1989) Pulmonary diseases in patients infected with the human immunodeficiency virus in Zimbabwe, Central Africa. Trans R Soc Trop Med Hyg 83: 694–697

    Google Scholar 

  • Medrano-González F, Alemán-Lorenzo A, Beato-Pérez JL (1986) Visceral leishmaniasis of fatal outcome associated with HTLV-III infection. Med Clin Barcelona 87: 780–781

    Google Scholar 

  • Millar A (1987) AIDS and the lung. Br Med J 294: 1334–1337

    CAS  Google Scholar 

  • Miller RF, Delaney S, Semple SJG (1989) Acute renal failure after nebulised pentamidine. Lancet 1: 1271–1272

    PubMed  CAS  Google Scholar 

  • Mitsuyasu R, Groupman J, Volberding P (1983) Cutaneous reaction to trimethoprim-sulfamethoxazole in patients with AIDS and Kaposi’s sarcoma. N Engl J Med 308: 1535–1536

    PubMed  CAS  Google Scholar 

  • Modigliani R, Bories C, Charpentier Y le, Salmerón M, Messing B, Galian A, Rambaud JC, Lavergne A, Cochand-Priollet B, Desportes I (1985) Diarrhoea and malabsorption in acquired immune deficiency syndrome: a study of four cases with special emphasis on opportunistic protozoan infestations. Gut 26: 179–187

    PubMed  CAS  Google Scholar 

  • Montalban C, Sevilla F, Moreno A, Nash R, Celma ML, Muñoz RF (1987) Visceral leishmaniasis as an opportunistic infection in the acquired immunodeficiency syndrome. J Infect 15: 247–250

    PubMed  CAS  Google Scholar 

  • Montalban C, Martinez-Fernandez R, Calleja JL, Garcia-Diaz J de D, Rubio R, Dronda F, Moreno S, Yebra M, Barros C, Cobo J, Martinez MC, Ruiz F, Costa JR (1989) Visceral leishmaniasis ( Kala-azar) as an opportunistic infection in patients infected with The Human Immunodeficiency Virus in Spain. Rev Infect Dis 11: 655–660

    Google Scholar 

  • Montgomery AB, Debs RJ, Luce JM, Corkery KJ, Turner J, Brunette EN, Lin ET, Hopewell PC (1987) Aerosolised pentamidine as sole therapy for Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome. Lancet 2: 480 - 483

    PubMed  CAS  Google Scholar 

  • Mottin D, Denis M, Dombret H, Rossert J, Mayaud C, Akoun G (1987) Role for steroids in treatment of Pneumocystis carinii pneumonia in AIDS. Lancet 2: 519

    PubMed  CAS  Google Scholar 

  • Newmark P (1988) Receding hopes of AIDS vaccines. Nature 333: 699

    PubMed  CAS  Google Scholar 

  • Nguyen-Dinh P, Greenberg AE, Ryder RW, Mann JM (1987) Absence of association between HIV seropositivity and Plasmodium falciparum malaria in Kinshasa, Zaire. 3rd International Conference on AIDS, Washington DC, Abstracts, p 22

    Google Scholar 

  • Nielsen PB, Goyot P, Mojon M (1986) The microscopic diagnosis of Pneumocystis carinii: an evaluation of the Gram, the Methylene Blue, and the Ziehl-Neelsen procedures. Acta Pathol Microbiol Scand [B] 94: 19–23

    CAS  Google Scholar 

  • Pape JW, Liautaud B, Thomas F, Mathurin J-R, Amand M-M A St, Boncy M, Pean V, Pamphile M, Laroche AC, Johnson WD (1983) Characteristics of the acquired immunodeficiency syndrome ( AIDS) in Haiti. N Engl J Med 309: 945–950

    PubMed  CAS  Google Scholar 

  • Penny D (1988) Origins of the AIDS virus. Nature 333: 494–495

    PubMed  CAS  Google Scholar 

  • Perre P van de, Rouvroy D, LePage P, Bogaerts J, Kestelyn P, Kayihigi J, Hekker AC, Butzler J-P, Clumeck N (1984) Acquired immunodeficiency syndrome in Rwanda. Lancet 2: 62–65

    PubMed  Google Scholar 

  • Petithory JC, Derouin F (1987) AIDS and strongyloidiasis in Africa. Lancet 1: 921

    PubMed  CAS  Google Scholar 

  • Petri WA, Ravdin JI (1987) Treatment of homosexual men infected with Entamoeba histolytica. N Engl J Med 315: 393

    Google Scholar 

  • Pierone G, Turett G, Masci JR, Nicholas P (1989) Inhaled pentamidine in Pneumocystis carinii pneumonia. Lancet 2: 559

    PubMed  CAS  Google Scholar 

  • Pilon VA, Echols RM, Celo JS, Elmendorf SL (1987) Disseminated Pneumocystis carinii infection in AIDS. N Engl J Med 316: 1410–1411

    PubMed  CAS  Google Scholar 

  • Piot P, Taelman H, Minlangu KB, Mbendi N, Ndangi K, Kalambayi K, Bridts C, Quinn TC, Feinsod FM, Wobin O, Mazebo P, Stevens W, Mitchell S, McCormick JB (1984) Acquired immuno deficiency syndrome in a heterosexual population in Zaire. Lancet 2: 65–69

    PubMed  CAS  Google Scholar 

  • Quinn TC, Mann JM, Curran JW, Piot P (1986) AIDS in Africa: an epidemiological paradigm. Science 234: 955–963

    PubMed  CAS  Google Scholar 

  • Reeve PA (1989) HIV infection in patients admitted to a general hospital in Malawi. Br Med J 298:1567–1568

    CAS  Google Scholar 

  • Rizzi M, Arici C, Bonaccorso C, Gavazzeni G (1988) Visceral leishmaniasis in a patient with human immunodeficiency virus. Trans R Soc Trop Med Hyg 82: 565

    PubMed  CAS  Google Scholar 

  • Rodgers VD, Fassett R, Kagnoff MF (1986) Abnormalities in intestinal mucosal T cells in homosexual populations including those with the lymphadenopathy syndrome and acquired immunodeficiency syndrome. Gastroenterology 90: 552–558

    PubMed  CAS  Google Scholar 

  • Rolston KVI, Hoy J, Mansell PWA (1986) Diarrhea caused by ‘non-pathogenic amebae’ in patients with AIDS. N Engl J Med 315: 192

    PubMed  CAS  Google Scholar 

  • Salata RA, Ravdin JI (1988) Human cell-mediated immune mechanisms directed against Entamoeba histolytica. In: Ravdin JI (ed) Amebiasis: human infection by Entamoeba histolytica. John Wiley, New York, pp 471–479

    Google Scholar 

  • Seale J (1989) Crossing the species barrier — viruses and the origins of AIDS in perspective. J R Soc Med 82: 519–523

    PubMed  CAS  Google Scholar 

  • Senaldi G, Cadeo G, Carnevale G, Perri G di, Carosi G (1986) Visceral leishmaniasis as an opportunistic infection. Lancet 1: 1094

    Google Scholar 

  • Sewankambo N, Mugerwa RD, Goodgame R, Carswell JW, Moody A, Lloyd G, Lucas SB (1987) Enteropathie AIDS in Uganda. An endoscopic, histological and microbiological study. AIDS 1: 9–13

    Google Scholar 

  • Sharp PM, Li W-H (1988) Understanding the origins of AIDS viruses. Nature 336: 315

    PubMed  CAS  Google Scholar 

  • Siegal FP, Lopez C, Fitzgerald PA, Shah K, Baron P, Leiderman IZ, Imperato D, Landesman S (1986) Opportunistic infections in acquired immune deficiency syndrome result from synergistic defects of both the natural and adaptive components of cellular immunity. J Clin Invest 78: 115–123

    PubMed  CAS  Google Scholar 

  • Simooya OO, Mwendapole RM, Siziya S, Fleming AF (1988) Relation between falciparum malaria and HIV seropositivity in Ndola, Zambia. Br Med J 297: 30–31

    Google Scholar 

  • Simpson TW (1984) Trichomoniasis. In: Strickland GT (ed). Hunter’s tropical medicine, 6th edn. Saunders, Philadelphia, pp 499–502

    Google Scholar 

  • Smith D, Gazzard B, Lindley RP, Darwish A, Reed C, Bryceson ADM, Evans DA (1989) Visceral leishmaniasis ( Kala-azar) in a patient with AIDS. AIDS 3: 41–43

    Google Scholar 

  • Smith PD, Lane CL, Gill VJ, Manischewitz JF, Quinnan GV, Fauci AS, Masur H (1988) Intestinal infections in patients with the acquired immunodeficiency syndrome (AIDS): etiology and response to therapy. Ann Intern Med 108: 328–333

    PubMed  CAS  Google Scholar 

  • Tanabe K, Fuchimoto M, Egawa K, Nakamura Y (1987) Use of Pneumocystis carinii genomic DNA clones for DNA hybridization analysis of infected human lungs. J Infect Dis 157: 593–596

    Google Scholar 

  • Thomas S, O’Doherty M, Bateman N (1990) Pneumocystis carinii pneumonia: aerosolised pentamidine gives effective prophylaxis. Br Med J 300: 211–212

    Google Scholar 

  • Torna E, Fournier S, Poisson M, Morisset R, Phaneuf D, Vega C (1989) Clindamycin with primaquine for Pneumocystis carinii pneumonia. Lancet 1: 1046–1048

    Google Scholar 

  • Tuazon CU, Labriola AM (1987) Management of infectious and immunological complications of acquired immunodeficiency syndrome (AIDS): current and future prospects. Drugs 33: 66–84

    PubMed  CAS  Google Scholar 

  • Tuazon CU, Delaney MD, Simon GL, Witorsch P, Varma VM (1985) Utility of gallium67 scintigraphy and bronchial washings in the diagnosis and treatment of Pneumocystis carinii pneumonia in patients with the acquired immune deficiency syndrome. Am Rev Resp Dis 132: 1087–1092

    PubMed  CAS  Google Scholar 

  • Verdejo J, Alvar J, Polo RM, Gonzälez-Lahoz JM (1987) Visceral leishmaniasis associated with positive anti-HTLV-III antibody. Rev Clin Esp 180: 221

    PubMed  CAS  Google Scholar 

  • Weissman I (1988) Approaches to an understanding of pathogenic mechanisms in AIDS. Rev Infect Dis 10: 385–398

    PubMed  CAS  Google Scholar 

  • Weller IVD (1987) Treatment of infections and antiviral agents. Br Med J 295: 200–203

    CAS  Google Scholar 

  • Wharton JM, Coleman DL, Wofsy CB, Luce M, Blumenfeld W, Hadley WK, Ingram-Drake L, Volberding PA, Hopewell PC (1986) Trimethoprim-sulfamethoxazole or pentamidine for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome: a prospective randomized trial. Ann Intern Med 105: 37–44

    PubMed  CAS  Google Scholar 

  • World Health Organisation (1986) Acquired immunodeficiency syndrome (AIDS): WHO/CDC case definition for AIDS. Weekly Epidemiol Ree 61: 69–76

    Google Scholar 

  • Wiley CA, Safrin RE, Davis CE, Lampert PW, Braude AI, Martinez AJ, Visvesvara GS (1987) Acanthameba meningoencephalitis in a patient with AIDS. J Infect Dis 155:130–133

    PubMed  CAS  Google Scholar 

  • Yebra M, Segovia J, Manzano L, Vargas J, Bernaldo-de-Quirós L (1988) Disseminated-to-skin kala-azar and the acquired immunodeficiency syndrome. Ann Intern Med 108: 490–491

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Hospital for Tropical Diseases, University College Hospital, UK

    G. C. Cook MD, DSc, FRCP, FRACP, FLS (Consultant Physician, Medical Specialist, Lecturer in Medicine, Professor of Medicine in the Universities of Zambia, Riyadh and Papua New Guinea)

  2. St Luke’s Hospital for the Clergy, UK

    G. C. Cook MD, DSc, FRCP, FRACP, FLS (Consultant Physician, Medical Specialist, Lecturer in Medicine, Professor of Medicine in the Universities of Zambia, Riyadh and Papua New Guinea)

  3. London School of Hygiene and Tropical Medicine, UK

    G. C. Cook MD, DSc, FRCP, FRACP, FLS (Consultant Physician, Medical Specialist, Lecturer in Medicine, Professor of Medicine in the Universities of Zambia, Riyadh and Papua New Guinea)

  4. Royal Nigerian Army, Nigeria

    G. C. Cook MD, DSc, FRCP, FRACP, FLS (Consultant Physician, Medical Specialist, Lecturer in Medicine, Professor of Medicine in the Universities of Zambia, Riyadh and Papua New Guinea)

  5. Makerere University, Uganda

    G. C. Cook MD, DSc, FRCP, FRACP, FLS (Consultant Physician, Medical Specialist, Lecturer in Medicine, Professor of Medicine in the Universities of Zambia, Riyadh and Papua New Guinea)

Authors
  1. G. C. Cook MD, DSc, FRCP, FRACP, FLS
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© 1990 Springer-Verlag London Limited

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Cook, G.C. (1990). ‘Opportunistic’ and Other Parasitic Infections in Relation to the Acquired Immune Deficiency Syndrome (AIDS). In: Parasitic Disease in Clinical Practice. The Bloomsbury Series in Clinical Science. Springer, London. https://doi.org/10.1007/978-1-4471-1769-8_2

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  • DOI: https://doi.org/10.1007/978-1-4471-1769-8_2

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1771-1

  • Online ISBN: 978-1-4471-1769-8

  • eBook Packages: Springer Book Archive

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