Anticoagulation and Extracorporeal Circuits: The Role of Prostacyclin
That the application of advanced technology in the intensive care unit is in the patient’s best interests is too often taken for granted by those unfamiliar with its use and unwary of possible harmful effects of such technology. For example, the pioneers of haemodialysis recall how the technique was nearly abandoned because it often caused hypotension. This was shown to be due to hypovolemia from unrecognized ultrafiltration and once understood, haemodialysis gradually became an accepted technique for the treatment of acute renal failure and later for chronic renal failure, although more subtle unwanted effects such as complement activation with pulmonary dysfunction and the effects of acetate in the dialysate on the heart have continued to emerge from time to time.
KeywordsAcute Renal Failure Cerebral Malaria Acute Liver Failure Fulminant Hepatic Failure Extracorporeal Circulation
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