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Bleeding in Acute Renal Failure

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Acute Renal Failure in the Intensive Therapy Unit

Part of the book series: Current Concepts in Critical Care ((CRITICAL CARE))

Abstract

A bleeding tendency, associated with renal failure, has been recognized since the eighteenth century (Riesman 1907), but its pathogenesis has only recently been elucidated. The availability of dialysis has reduced the incidence of bleeding episodes, and the early use of dialysis in acute and chronic renal failure has been particularly effective in this respect. There certainly exists a difference in the severity of bleeding between patients suffering from acute renal failure compared with those with chronic renal failure. The bleeding tendency in chronic renal failure is usually mild; it is restricted to mucocutaneous sites, being manifest as epistaxis, petechiae and increased bleeding from wounds. This is different from severe haemorrhage, which may occur in patients with acute renal failure; severe bleeding may also occur in patients with end-stage renal failure when they are dialysed for the first time. The additional effects of drugs, required for the adequate treatment of patients suffering from renal failure, may further contribute to any bleeding tendency, as will be discussed. For the sake of clarity, the bleeding tendency caused by chronic renal failure, acute renal failure and dialysis will be considered separately.

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Authors
  1. K. Andrassy
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Editor information

Editors and Affiliations

  1. Department of Intensive Care, Guy’s Hospital, St Thomas St, SE1 9RT, London, UK

    David Bihari MA, MRCP (Director of Intensive Care Services) (Director of Intensive Care Services)

  2. Department of Renal Medicine, Institute of Urology, UCMSM, St Philip’s Hospital, Sheffield St, WC2A 2EX, London, UK

    Guy Neild MD, FRCP (Senior Lecturer in Nephrology) (Senior Lecturer in Nephrology)

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© 1990 Springer-Verlag Berlin Heidelberg

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Andrassy, K. (1990). Bleeding in Acute Renal Failure. In: Bihari, D., Neild, G. (eds) Acute Renal Failure in the Intensive Therapy Unit. Current Concepts in Critical Care. Springer, London. https://doi.org/10.1007/978-1-4471-1750-6_21

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  • DOI: https://doi.org/10.1007/978-1-4471-1750-6_21

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1752-0

  • Online ISBN: 978-1-4471-1750-6

  • eBook Packages: Springer Book Archive

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