The Management of the Side Effects of Cytotoxic Drugs
The ability of cytotoxic drugs to cure malignant disease is limited by two factors, drug resistance of tumour cells and the toxic effects of treatment on normal tissues. A number of techniques have been developed in an attempt to overcome the problems created by drug toxicity, in the hope of allowing higher doses of cytotoxics to be given, thereby increasing the chance of cure. Before considering the prevention and management of specific side effects it is important to realise that the very considerable hazards involved in the use of cytotoxic agents may be minimised by taking a few routine precautions.
KeywordsToxicity Dexamethasone Doxorubicin Cyclophosphamide Thrombocytopenia
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