Imaging with mIBG has the advantage that the abnormality is seen as an area of increased radioactivity in a background of less activity, facilitating detection and interpretation. The mIBG images have been shown, by many centres, to demonstrate lesions not visible on other modalities; therefore mIBG scintigraphy is now accepted by most paediatric oncologists as potentially a very valuable additional technique for accurate staging of neuroblastoma, provided high-quality images are produced. Special imaging techniques and optimal conditions are required to reduce the number of poor-quality images as these give equivocal results.
KeywordsIodine Sodium Chloride Radionuclide Iodide Noradrenaline
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