A Computer-Controlled Hyperthermia System
Hyperthermia, raised temperature, has been used as a means of treating cancer for centuries. Hippocrates (400 bc) and Galen (200 bc) used red-hot irons to treat small tumours. Much later, after the Renaissance, there are many reports of spontaneous tumour regression in patients with fevers produced by erysipelas, malaria, smallpox, tuberculosis and influenza. These illnesses produce fevers of about 40°C which last for several days. Temperatures of at least 40°C were found to be necessary for tumour regression. Towards the end of the nineteenth century pyrogenic bacteria were injected into patients with cancer. In 1896, Coley used a mixture of erysipelas and B. prodigeosus toxins, with some success.
KeywordsTarget Temperature Thermocouple Junction Thermal Dose Steady Phase Forward Power
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- Conner WG (1977) Prospects for hyperthermia in human cancer therapy. II. Implications of biological and physical data for applications of hyperthermia in man. Radiology 123: 497–503Google Scholar
- Dewey WC (1976) Cellular responses to combinations of hyperthermia and radiation. Radiology 123: 463–74Google Scholar
- Hand JW, James JR (1986) Physical techniques in clinical hyperthermia. Research Studies Press, Letchworth, England.Google Scholar
- Westermark N (1927) The effect of heat upon rat tumours. Skand Arch Physiol 52: 257–322Google Scholar