Abstract
The soft tissues of the body, including those of the central nervous system, are poorly demonstrated on plain X-ray films and the need for agents which would enhance these images was perceived in the very earliest days of radiology (Wallingford 1953; Bull 1961). The story of the development of such agents in fact constitutes a fascinating sub-plot in the history of the subject. The rapid post-war development of neurosurgical techniques was a powerful impetus for further improvements in the potential of neuroradiological imaging and had a significant influence on the development of safer contrast agents (Bull 1961).
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References
Abbott KH, Gray JR, Goodall RJ (1952) Clinical complications of cerebral angiography. J Neurosurg 9:258–274
Ahlgren P (1972) Dimer-X. A new contrast medium for lumbar myelography without spinal anaesthesia. Acta Radiol [Diagn] (Stockh) 13:753–761
Ahlgren P (1980) Early and late side-effects of water soluble contrast media for myelography and cisternography: a short review. Invest Radiol 15:S264–S266
Albertson K, Doppman JL (1974) Meglumine diatrizoate v iothalamate: comparison of seizure-inducing potential, Br J Radiol 47:265–267
Angiari P, Crisi G, Merli GA (1974) Aphasia and right hemi-plegia after cervical myelography with Amipaque. A case report. Neuroradiology 26:61–63
Ansell G, Tweedie MCK, West CR, Evans P, Couch L (1986) The current status of reactions to intravenous contrast media. Invest Radiol 15:S32–S39
Arnell S, Lidstrom F (1931) Myelography with Skiodan (Abrodil). Acta Radiol 12:287–291
Baker RA, Hillman BJ, McLennan JE, Strand RD, Kaufman SM (1978) Sequelae of metrizamide myelography in 200 examinations. AJR 130:499–502
Bertoni JM, Alexander GM, Schwartzman RJ (1980) Metrizamide competitively inhibits hexokinase. In: Duvoisin RC (ed) Transactions of the American Neurological Association, vol 105. Springer, Berlin, Heidelberg, New York, pp 218–220
Bertoni JM, Schwartzman RJ, Van Horn G, Partin J (1981) Asterixis and encephalopathy following metrizamide myelography: Investigation into possible mechanisms and review of the literature. Ann Neurol 9:366–370
Boijsen E, Lindholmer E (1971) Serious complications from myelography with meglumine iothalamate. An account of 324 lumbar myelographies together with a description of 2 cases of severe leg cramp. Nord Med 85:520–522
Boyd JT, Langlands AO, MacCabe JJ (1968) Long-term hazards of Thorotrast. Br Med J ii:517–521
Brendler SJ, Hayes GJ (1959) Hypaque in cerebral angiography: report of complications in 617 angiograms. J Neurosurg 16:454–460
Broman T, Olsson O (1984) The tolerance of cerebral blood vessels to a contrast medium of the diodrast group. Acta Radiol 30:326–342
Bryan RN, Hershkowitz N (1982) Intracellular effects of radiographic contrast agents on the rat-hippocampus (abstr). AJNR 3:93
Bull JWD (1961) History of neuroradiology. The presidential address delivered at the British Institute of Radiology, 20 Oct 1960. BrJ Radiol 34:69–84
Caille JM, Guibert-Tranier F, Howa, JM, Billerey J, Calabet A, Piton J (1980) Cerebral penetration following metrizamide myelography, J Neuroradiol 7:3–12
Camp JD (1950) Contrast myelography: past and present. Radiology 54:477–505
Cornell SH (1969) Spasticity of the lower extremities following abdominal aortography. Radiology 93:377–379
Cristi G, Scialfa G, Di Pierro G, Tassoni A (1974) Visual loss: a rare complication following oil myelography. Case report and review of the literature. Neuroradiology 7:287–290
Crocker EF, Zimmerman RA, Phelps ME, Kuhl DE (1976) The effects of steroids on the extravascular distribution of radiographic contrast material and technetium pertechnetate in brain tumours as determined by computer tomography. Radiology 119:471–475
Cronquist S (1983) Iohexol in cerebral angiography. Survey and present state. Acta Radiol [Suppl] (Stockh) 36:135–139
Dahlstrom K (1984) Summary of US and European intra-vascular experience with iohexol. Presented at “A worldwide clinical assessment of a new contrast medium, iohexol”, Boca Raton, Fla, May 1984, ppSl17–S120
Dandy WE (1919) Roentgenography of the brain after the injection of air into the spinal canal. Ann Surg 70:397–403
Dandy WE (1925) The diagnosis and localisation of spinal cord tumours. Ann Surg 81:223–227
Dawson P (1985) Chemotoxicity of contrast media and clinical adverse effects; a review. Invest Radiol 20:S84–S91
Dawson P (1987) Iodinated intravascular contrast agents; a review. J Intervent Radiol 2:51–58
Dawson P, Edgerton D (1983) Contrast media and enzyme inhibition-1 cholinesterase. Br J-Radiol 56:653–656
Dawson P, Howell M (1986) The non-ionic dimers; a new class of contrast agents. Br J Radiol 59:987–991
Dawson P, Harrison MJG, Weisblat E (1983a) Effect of contrast media on red cell filtrability and morphology. Br J Radiol 56:707–710
Dawson P, Grainger RG, Pitfield J (1983b) The new low osmolar contrast media-a simple guide. Clin Radiol 34:221–226
Dawson P, Penhaligon M, Smith E, Saunders J (1987) Iodinated contrast agents as radio-sensitisers. Br J Radiol 60:201–203
Dean PB, Kormano M (1977) Intra-arterial bolus of 125I labelled meglumine diatrizoate. Early extravascular distribution. Acta Radiol [Diagn] (Stokh) 18:425–432
Djindjian R (1969) Arteriography of the spinal cord. Am J Roentgenol Rad Ther Nucl Med 197:461–478
Dormer FR (1969) Effects of diuretics on cerebrospinal fluid formation and potassium movement. Exp Neurol 24:54–64
Drayer B, Ross M, Allen S, France R, Bates M (1984) lotrol myelography: initial clinical trial. Invest Radiol 19:S141
Dullerud R, Morland TJ (1976) Adhesive arachnoiditis after lumbar radiculography with Dimer-X and Depo-Medrol. Radiology 119:153–155
Ekholm SE (1985) Iohexol versus metrizamide in studies of glucose metabolism. A survey. Invest Radiol 20:S 18–21
Ekholm SE, Reece K, Coleman, DK Jr, Fischer H (1983) Metrizamide-a potential in vivo inhibitor of glucose metabolism. Radiology 147:119–121
Eldevik OP, Haughton VM (1978) The effect of hydration of the acute and chronic complications of aqueous myelography. An experimental study. Radiology 129:713–714
Eldevik OP, Nakken KO, Haughton VM (1978a). The effect of dehydration on the side effects of metrizamide myelography. Radiology 129:715–716
Eldevik OP, Haughton VM, Ho KC, Williams AL, Unger GF, Larson SJ (1978b) Ineffectiveness of prophylactic intrathecal methylprednisolone in myelography with aqueous media. Radiology 129:99–101
Epsen F (1966) Spinal cord lesion as a complication of abdominal aortography. Acta Radiol [Diagn] (Stockh) 4:47–61
Erickson TC, Van Baaren HH (1953) Late meningeal reaction to ethyl iodophenyl undecylate used in myelography: report of a case that terminated fatally. JAMA 153:636–639
Feigelson HH, Ravin HA (1965) Transverse myelitis following selective bronchial arteriography. Radiology 85:663–665
Feny DW, Gooding R, Standefer JC, Weise GM (1973) Effect of Pantopaque myelography on cerebrospinal fluid reactions. J Neurosurg 38:167–171
Fischer HW, Eckstein JW, Perret G (1962) Comparison of cardiovascular effect of contrast media in cerebral angiography in man. J Neurosurg 19: 943–946
France RD, McCracken J (1984) Delirium following metrizamide myelography. Psychosomatics 25:338–339
French L, Blake PS (1950) Complications following the use of neo-iopax in cerebral angiography. Am J Roentgenol Rad Ther Nucl Med 64: 816–818
Gabrielson TO, Geparski SS, Knake JE, Latack JT, Yang PJ, Hoff JT (1984) Iohexol versus metrizamide for lumbar myelography: double-blind trial. AJR 142:1047–1049
Galle G, Huk W, Arnold K (1984) Psychopathometric demonstration and quantification of mental disturbances following myelography with metrizamide and iopamidol. Neuroradiology 26:229–233
Gardeur D, Lautrou J, Millard JC, Berger N, Matzger J (1980) Pharmacokinetics of contrast media: experimental results in dogs and man with CT implications. J Comput Assist Tomogr 4:178–185
Gelmers HJ (1979) Adverse side effect of metrizamide in myelography. Neuroradiology 18: 118–123
Golman K (1979) The blood-brain barrier effects of non-ionic contrast media with and without addition of Ca2+ and Mg2+. Invest Radiol 14:305–308
Gonsette R (1971) An experimental and clinical assessment of water soluble contrast medium in neuroradiology. A new medium: Dimer-X. Clin Radiol 22:44–56
Gonsette R (1973) Biologic tolerance of the central nervous system to metrizamide. Acta Radiol [Suppl] (Stockh) 335:25–44
Gonsette R (1978) Animal experiments and clinical experiences in cerebral angiography with a new contrast agent (ioxaglic acid) with a low hyperosmolality. Ann Radiol 21:271–273
Gonsette R, Brucher JM (1980) Neurotoxicity of novel water soluble contrast media for intra-thecal application. Invest Radiol 15:S254–S259
Grainger RG (1980) Osmolality of intravascular radiological contrast media. Br J Radiol 53:739–746
Grainger RG (1982) Intravascular contrast media-the past, the present and the future. Br J Radiol 55:1–18
Greenberg MK, Vance SC (1980) Focal seizure disorder complication of iodophendylate myelography (letter). Lancet i:312–313
Gulati AN, Guadagnoil DA, Quigley JM (1981) Relationship of side effects to patient position during and after metrizamide lumber myelography. Radiology 141:113–116
Hammer B, Lackner W (1980) Iopamidol, a new non-ionic hydrosoluble contrast medium for neuroradiology. Neuroradiology 19:119–121
Harnish PP, Di Stefano V (1984) Decreased CSF production by Intravenous sodium diatrizoate. Invest Radiol 19:318–323
Harnish PP, Di Stefano V (1985) Pharmacological action of radiographic contrast media reduced CSF production in the dog. J Pharmacol Exp Ther 232:88–93
Harnish PP, Northington RK, Di Stefano V, Banarjee SP (1986) Mechanisms of decreased cerebrospinal fluid production by radiographic contrast media: role of adenylate cyclase activation. J Pharmacol Exp Ther 236:464–469
Harnish PP, Northington FK, Samuel KA (1988) Iohexol Inhibits adenylate cyclase. Invest Radiol 23:139–142
Harvey JP, Freiberger RF, Werner G (1961) Clinical and experimental observations with methiodal, an absorbable myelo-graphic contrast agent. Clin Pharmacol Ther 2:610–614
Haughton VM (1976) Changes of arachnoiditis after metrizamide myelography: experimental work in monkeys. Myelography and the water soluble contrast medium. University of Wisconsin, Madison, 26 March
Haughton VM (1985) Intrathecal toxicity of iohexol versus metrizamide. Survey and current state. Invest Radiol 20:S14–S17
Haughton VM, Ho KC (1980) Arachnoiditis from myelography with iopamidol, metrizamide and iocarmate compared in the animal model. Invest Radiol 15:S267–S269
Haughton VM, Ho KC, Larson S et al. (1977) Arachnoiditis following intrathecal injection of blood and aqueous contrast media. Acta Radiol [Suppl] (Stockh) 355:373–378
Haughton VM, Ho KC, Larsen SJ, Unger GF, Correa-Pax F (1978) Comparison of arachnoiditis produced by meglumine iocarmate and metrizamide myelography in an animal model. AJR 131:129–132
Henson RA, Parsons M (1967) Ischaemic lesions of the spinal cord: an illustrated review. QJ Med 36:205–222
Hershkowitz N, Bryan RN (1982) Neurotoxic effects of water-soluble contrast agents on rat hippocampus extracellular recordings. Invest Radiol 17:271–275
Higgins CB, Schmidt WS (1979) Identification and evaluation of the contribution of the chemoreflex in the hemodynamic response to intracarotid administration of contrast materials in the conscious dog: comparison with the response to nicotine. Invest Radiol 14:438–446
Hilal SK (1966a) Haemodynamic responses in the cerebral vessels to angiographic contrast media. Acta Radiol [Diagn] (Stockh) 5:211–231
Hilal SK (1966b) Haemodynamic’changes associated with intra-arterial injection of contrast media. Radiology 86:615–633
Hilal SK (1974) Cerebral hemodynamics assessed by angiography. In: Newton TH, Potts DG (eds) Radiology of the skull and brain. CV Mosby, St Louis, pp 1067–1085
Hindmarch T, Grepe A, Widen L (1975) Metrizamide-phen-othiazine interaction: report of a case with seizures following myelography. Acta Radiol [Diagn] (Stockh) 16:129–134
Hoppe JO (1959) Some pharmalogical aspects of radiopaque compounds. Ann NY Acad Sci 78:727–739
Howell MJ, Dawson P (1985) Contrast media and enzyme inhibition. II Mechanisms. Br J Radiol 58:845–848
Howieson J (1974) Complications of cerebral angiography. In: Newton TH, Potts DG (eds) Radiology of skull and brain: Angiography, CV Mosby, St Louis, Chap. 53
Hughes R (1953) Chronic changes in the central nervous system following Thorotrast ventriculography. Proc R Soc Med 46:191–195
Ingvar DH (1957) EEG during cerebral angiography. Acta Radiol 47:181–184
Irastam L, Sellden U (1976) Adverse effects of lumbar myelography with Amipaque and Dimer-S. Acta Radiol [Diagn] (Stockh) 17:145–159
Irastam L, Sundstrom R, Sigstedt B (1974) Lumbar myelography and adhesive arachnoiditis. Acta Radiol [Diagn] (Stockh) 15:356–368
Jacobaeus HG (1921) On insufflation of air into the spinal canal for diagnostic purposes in cases of tumors in the.spinal canal. Acta Med Scand 55:555–564
Jaeger R (1950) Irritating effect of iodized vegetable oils on the brain and spinal cord when divided into small particles. Arch Neurol Psychiatry 64:715–719
Jeppson PG, Olin T (1970) Neurotoxicity of Roentgen contrast media. Study in the blood-brain barrier in the rabbit following selective injection of contrast media into the internal cerebral artery. Acta Radiol [Diagn] (Stockh) 10:17–34
Jones DF (1980) Postoperative convulsions due to iophendylate (Myodil). Report of a case and review of the causes of postoperative convulsions. Anaesthesia 35:50–56
Kaada B (1973) Transient EEG abnormalities following lumbar myelography with metrizamide. Acta Radiol [Suppl] 33:380–386
Kachel R, Ritter H, Schiffmann R, Schumann E (1980) Complication following cerebral angiography: Report on 4,181 cerebral angiographies. Zentralbl Chir 105:504–512
Kendall BE (1964) Cerebral angiography using Conray. Br J Radiol 37:581–589
Kendall BE, Pullicino P (1980) Intravascular contrast injection in ischamic lesions. Neuroradiology 19:241–243
Kendall B, Schneidau A, Stevens J, Harrison M (1983) Clinical trial of Iohexol for lumbar myelography. Br J Radiol 56:539–542
Kido DK, Gordon-Potts D, Bryan NR et al. (1985) Iohexol cerebral angiography. Multicentre clinical trial. Invest Radiol 30:S55–S57
Koppejan EH, Bejeer N, Bosch DA, Vencken LM (1981) Organic psychosyndrome correlated with high density of grey matter on CT following metrizamide cervical myelography. Clin Neurol Neurosurg 83:63–66
Kun M, Alwaskiak J, Gronska J (1978) Morphological changes in the CNS after Dimer-X ventriculography. Neuroradiology 15:99–106
Kwentus JA, Silverman JJ, Sprague M (1984) Manic syndrome after metrizamide myelography. Am J Psychiatry 14: 700–702
Labauger R, Cailar J, Xhardex M et al. (1968) Cortical blindness after cerebral angiography; reversibility under hyperbaric oxygen therapy. Rev Neurol (Paris) 118:283–289
Lalli AF (1980) Contrast media reactions: Data analysis and hypothesis. Radiology 134:1–16
Lalli AF, Greenstreet R (1981) Reactions to contrast media: testing the CNS hypothesis. Radiology 138:47–49
Lamb JT (1984) A comparison of Iopamidol and Iohexol for myelography. Neuroradiology 26:157
Lefft HH, Maclean JA Jr (1942) Visualization of the brain and spinal cord with diodothyrosine-gelatin contrast medium, including observation on the fate of this material. Arch Neurol Psychiatry 48:343–347
Lindblom K (1947) Complications of myelography by Abrodil. Acta Radiol 28:69–73
Lindgren P (1958) Blood pressure and heart rate responses in carotid angiography with sodium actrizoat. Acta Radiol 50:160–174
Lindgren P (1959) Carotid angiography with tri-iodobenzoic acid derivatives: A comparative experimental study of the effects on the systemic circulation in cats. Acta Radiol 51:353–362
Luce JC, Leith W, Burrage WC (1951) Pantopaque meningitis due to hypersensitivity. Radiology 57:878–881
Lundervold A, Engeset A (1969) Electroencephalographic and electrocardiographic studies of complications in cerebral angiography. Acta Radiol [Diagn] (Stockh) 9:399–406
Lynch PR, Harrington GJ, Michie C (1969) Cardiovascular reflexes associated with cerebral angiography. Invest Radiol 4:156–160
Mani RL, Eisenberg RL (1978) Complication of catheter cerebral arteriography: analysis of 5,000 procedures. III. Assessment of arteries injected, contrast medium used, duration of procedure and age of patient. AJR 131:871–874
Margolis G, Griffin AT, Kenan PD et al. (1959) Contrast medium injury to the spinal cord: the role of altered circulatory dynamics. J Neurosurg 16:390–406
Masdeu JC, Glista GG, Rubino FA, Martinex-Lage JM, Marani E (1983) Transient motor aphasia following metrizamide myelography. AJNR 4:200–202
Mason MS, Raof J (1962) Complications of Pantopaque myelography: case report and review. J Neurosurg 19:302–311
McChesney EW, Hoppe JO (1957) Studies of the tissue distribution and execretion of sodium diatrizoate in laboratory animals. Am J Roentgenol Rad Ther 78:137–144
McClennan BL, Becker JA (1971) Cerebrospinal fluid transfer of contrast material at urography. AJR 113:427–432
McLennan JE (1973) Prevention of post-myelographic post-pneumoencephalographic headache by single dose intrathecal methyl-prednisolone acetate. Headache 13:39–48
Melartin E, Tuohimaa PJ, Dabb R (1970) Neurotoxicity of iothalamate and diatrizoates. I. Significance of concentration and cation. Invest Radiol 5:13–21
Moniz E (1927) L’encephalographie arterielle, son importance dans la localisation des tumeurs cerebrales. Rev Neurol 2:72–90
Morris TW, Francis M, Fisher HW (1979) A comparison of the cardiovascular responses to carotid injections of ionic and nonionic contrast media. Invest Radiol 14:217–223
Muetzel W, Speck U (1980) Pharmacokinetics and biotransformation of iohexol in the rat and the dog. Acta Radiol [Suppl] 362:87–92
Muetzel W, Press W-R, Weinmann HJ (1984) Preclinical experience with iotrol. Invest Radiol 19:S140–S141
Murphy DJ (1973) Cerebrovascular permeability after meglumine iothalamate administration. Neurology 23:926–936
Neuwelt EA, Barnett PA, Bigner DD, Frenkel EP (1982) Effects of adrenal cortical steroids and osmotic blood-brain barrier opening on methotrexate delivery to gliomas in the rodent: the factor of the blood-brain barrier. Proc Natl Acad Sci USA 79:4420–4423
Newhouse JH (1977) Fluid compartment distribution of intravenous iothalamate in the dog. Invest Radiol 12:364–367
Nielsen H (1975) Case reports: epileptic seizures following cervical myelography, Neuroradiology 10:59–60
Nishikawa M, Yonekawa Y (1976) Intracisternal dimer X: toxicity and prophylaxis. Neuroradiology 11: 61–65
Northington JW, Biery DN, Lawrence TG (1982) Intrathecal Dextrose to prevent seizures after metrizamide myelography in dogs. Invest Radiol 17:282–283
Occhiogrosso M, Troccoli V, Vailati G (1979) A rare complication following iodized myelography: Late blindness. Case report. Acta Neurol (Napoli) 34:76–78
Oftedal SI (1977) Toxicity of water soluble contrast media injected suboccipitally in cats. Acta Radiol [Suppl] 335:84–92
Oftedal SI (1982) Meningeal reactions to water soluble contrast media: a comparison of iophendylate and metrizamide in experimental animals. Radiology 143:699–702
Oftedal SI, Kayed K (1983) Epileptogenic effects of water soluble contrast media: an experimental investigation in rabbits. Acta Radiol [Suppl] 335:45–56
Perlman EM, Barry D (1984) Bilateral sixth nerve palsy after water soluble contrast myelography. Letter. Arch. Ophthalmol 102:986
Peroutka SJ, Ullrich CG, Fisher RS, Suss RA, Brooks BR (1982) Transient areflexia and quadriplegia following metrizamide myelography (Letter). Ann Neurol 12:406–407
Petrovitch M (1981) Radiological evaluation of the spinal cord. CRC Press, Boca Raton
Raininko R (1979) Role of hypertonicity in the endothelial injury caused by angiographic contrast media. Acta Radiol [Diagn] (Stockh) 20:410–416
Ramsey GH, French JD, Strain WH (1944) Iodinated organic compounds as contrast media for radiographic diagnosis. IV. Pantopaque myelography. Radiology 43:236–241
Rapoport SI, Levitan H (1974) Neurotoxicity of X-ray contrast media. Relation to lipid solubility and blood brain barrier permeability, AJR 122:186–193
Rapoport SI, Thompson HK, Bidinger JM (1974) Equiosmolal opening of the blood-brain barrier in the rabbit by different contrast media. Acta Radiol [Diagn] (Stockh) 15:21–32
Reed DJ (1968) The effects of actazolamide on pentobarbitol sleep-time and cerebrospinal fluid flow of rats. Arch Int Phar-macodyn 171:206–215
Reed DJ (1969) The effect of furosemide on cerebrospinal fluid flow in rabbits. Arch Int Pharmacodyn 178:324–330
Reisner H, Samec P, Zeiler K (1980) On the complication rate of cerebral angiography. Neurosurg Rev 3:23–29
Rolfe EB, Maguise PD (1980) The incidence of headache following various techniques of metrizamide myelography. Br J Radiol 53:840–844
Ropper AH, Chiappa K, Young RR (1978) The effect of metrizamide on the EEG: A prospective study in 62 cases. Trans Am Neurol Assoc 103:159–162
Rosenbaum AE, Baker RA (1984) Pneumomyelography. In: Shapiro R (ed) Myelography, Yearbook Medical Publishers, Chicago
Rubin RC, Henderson ES, Ommaya AK, Walker MD, Rail DP (1966) The production of cerebrospinal fluid in man and its modification by actazolamide. J Neurosurg 25:430–436
Sage MR, Wilcox J, Evill CA, Benness GT (1982a) Brain parenchyma penetration by intrathecal ionics and non-ionic contrast media. AJNR 3:481–483
Sage MR, Wilcox, J, Evill CA, Benness GT (1982b) Comparison and evaluation of osmotic blood brain barrier disruption following intracarotid mannitol and methylglucamine iothalamate. Invest Radiol 17:276–281
Schober R (1964) Roentgen-Kontrastmittel und Liquor-Raum. Springer, Berlin, Heidelberg, New York
Shaw DD, Gansmo TB, Dahlstrom K (1985) Iohexol. Summary of North American and European clinical trials in adult lumbar, thoracic and cervical myelography with a new nonionic contrast medium. Invest Radiol 20:S44–S50
Shehadi WH, Toniolo G (1980a) Adverse reactions to intra-vascularly administered contrast media. AJR 124:145–152
Shehadi WH, Toniolo G (1980b) Adverse reactions to contrast media. Radiology 137:229–302
Sicard JA, Forestier JE (1922) Methode generale d’exploration radiologique par l’huile iodie (lipidoil). Bull Soc Med Hop Paris 46:463–469
Skalpe IO (1976) Adhesive arachnoiditis following lumbar radic-ulography with water soluble contrast agents. Radiology 121:647–651
Smith MA, Laguna JF (1980) Confusion, dysphasia, and asterixis following metrizamide myelography. Can J Neurol Sci 7:309–311
Sovak M, Siefert HM, Ranganathan R (1980) Combined methods for assessment of neurotoxicity. Testing of new nonionic radiographic media. Invest Radiol 15:S248–S253
Sovak M, Ranganathan R, Speck U (1982a) Nonionic dimer: Development and initial testing of an intrathecal contrast agent. Radiology 142:115–118
Sovak M, Siefert HM, Ranganathan R (1982b) Combined methods for assessment of neurotoxicity: Testing of new nonionic radiographic media. Invest Radiol 15:6
Stack JP, Antoun NM, Jenkins JPR, Metcalfe RA, Isherwood I (1988) Gadolinium DTPA as a contrast agent in magnetic resonance imaging of the brain. Neuroradiology 30: 145–154
Steinhausen TB, Dungan CE, Furst JB et al. (1944) Iodinated organic compounds as contrast media for radiographic diagnosis. III. Experimental and clinical myelography with ethyl iodophenylundecylate (Pantopaque). Radiology 43:230
Strain WH (1971) Radiocontrast agents for neuroradiology. In: Knoefel PK (ed) Encyclopaedia of contrast media, vol 11. Pergamon Press, Oxford, p 369
Strain WH, French JD, Jones GE (1946) Iodinated organic compounds as contrast media for diagnosis. Escape of Pantopaque from intracranial subarachnoid space of dogs. Radiology 47:47–50
Studdard WE, Davis DO, Young SW (1981) Cortical blindness after cerebral angiography. A case report. J Neurosurg 54:240–244
Suzuki S, Kawaguchi S, Mita R, Ito K, Iwabuchi T (1976a) Ventriculography with methylglucamine iocarmate (Dimer-X). Experimental and clinical study. Neurol Surg (Tokyo) 3:849–858
Suzuki S, Kawaguchi S, Mita R, Iwabuchi T (1976b) Ventriculography with methylglucamine iocarmate (Dimer-X). Experimental and clinical study. Acta Neurochir (Wien) 33:219–223
Taren JA (1960) Unusual complication following Pantopaque myelography. J Neurosurg 17:323–326
Thomas SF, Heary GW, Kaplan HS (1951) Hepatolienography: Past, present and future. Radiology 57:669–683
Usbeck W, Assmann H (1977) value of Dimer-S myelography in the diagnosis of lumbar intravertebral disk lesions. Zentralbl Neurochir 38:165–174
Waldron RL, Bridenbaugh RB, Dampsey EW (1974) Effect of angiographic contrast media at cellular level in the brain: hypertonic vs chemical action. AJR 122:469–476
Wales LR, Nov AA (1981) Transient global amnesia: Complication of cerebral angiography. AJNR 2:275–277
Wallingford VH (1953) The development of organic iodide compounds as X-ray contrast media. J Am Pharmacol Assoc 42:721–728
White WB (1984) Metrizamide meningitis. South Med J 77:88–89
Wolf GL, Popp C (1984) NMR. A primer for medical imaging. Slack Incorporated, New Jersey
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Dawson, P. (1990). Contrast Media and the Central Nervous System. In: Butler, P. (eds) Imaging of the Nervous System. Clinical Medicine and the Nervous System. Springer, London. https://doi.org/10.1007/978-1-4471-1637-0_12
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