Inverted papilloma is an uncommon epithelial tumour of the nose and paranasal sinuses which has been the subject of much interest and considerable debate since it was first described by Ringertz (1938). Although the earliest references to nasal papilloma were by Ward (1854) and Billroth (1855), Ringertz first drew attention to the “inverted” nature of the tumour and since then considerable controversy has surrounded the nomenclature, natural history and treatment of these lesions.


Nasal Cavity Paranasal Sinus Nasal Obstruction Adenoid Cystic Carcinoma Invert Papilloma 
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  1. Acheson ED, Hadfield E, Macbeth RG (1967) Carcinoma of the nasal cavity and accessory sinuses in woodworkers. Lancet I:311–312CrossRefGoogle Scholar
  2. Batsakis JG (1970) Mucous gland tumors of the nose and paranasal sinuses. Ann Otolaryngol 79:557–562Google Scholar
  3. Batson OV (1940) Formation of the vertebral veins and their role in the spread of metastases. Ann Surg 112:138–147PubMedCrossRefGoogle Scholar
  4. Billroth T (1855) Ueber dem Bau des Schleimpolyp. Reimer, Berlin, p 11Google Scholar
  5. Billroth T (1859) Beobachtungen über Geschwulste der Speicheldrüsen. Virchows Arch Pathol Anat Histol 17:357–375CrossRefGoogle Scholar
  6. Brown B (1964) The papillomatous tumours of the nose. J Larngyol Otol 78:889–905Google Scholar
  7. Churchill HR (1934) Histological differentiation between certain dentigerous cysts and ameloblastoma. Dental Cosmos 76:1173–1178Google Scholar
  8. Eneroth CM, Martensson G, Thulin A (1961) Profuse epistaxis in hypernephroma metastasis. Acta Otolaryngol 53:546–550CrossRefGoogle Scholar
  9. Friedmann I, Osborn DA (1965) Metastatic tumours in the ear, nose and throat region. J Laryngol Otol 79:576–591PubMedCrossRefGoogle Scholar
  10. Friedmann I, Osborn DA (1982) Pathology of granulomas and neoplasms of the nose and paranasal sinuses. Churchill Livingstone, EdinburghGoogle Scholar
  11. Garrett MJ (1959) Metastatic tumours of the paranasal sinuses simulating primary growths. J Fac Radiol (Lond) 10:151–155CrossRefGoogle Scholar
  12. Hadfield EH (1970) A study of adenocarcinoma of the paranasal sinuses in woodworkers in the furniture industry. Ann R Coll Surg Engl 46:301–319PubMedGoogle Scholar
  13. Hadfield EH, Macbeth RG (1971) Adenocarcinoma of ethmoids in furniture workers. Ann Otol Rhinol Laryngol 80:699–703PubMedGoogle Scholar
  14. Harrison DFN (1976) Malignant melanoma arising in the nasal mucous membrane. J Laryngol Otol 90:993–1005PubMedGoogle Scholar
  15. Harrison MS, Doey WD, Osborn DA (1964) Intranasal metastasis from renal carcinoma. J Laryngol Otol 78:103–107PubMedCrossRefGoogle Scholar
  16. Holdcraft J, Gallagher JC (1969) Malignant melanomas of the nasal and paranasal sinus mucosa. Ann Otol Rhinol Laryngol 78:1–20Google Scholar
  17. Hyams VJ (1971) Papillomas of the nasal cavity and paranasal sinuses. Ann Otol Rhinol Laryngol 80:192–206PubMedGoogle Scholar
  18. Kramer R, Som ML (1935) True papilloma of the nasal cavity. Arch Otolaryngol 22:22–43CrossRefGoogle Scholar
  19. Lund VJ (1982) Malignant melanoma of the nasal cavity and paranasal sinuses. J Laryngol Otol 96:347–355PubMedGoogle Scholar
  20. Lund VJ, Lloyd GAS (1984) Radiological changes associated with inverted papilloma of the nose and paranasal sinuses. Br J Radiol 57:455–461PubMedCrossRefGoogle Scholar
  21. Mabery TE, Devine KD, Harrison EG (1965) The problem of malignant transformation in a nasal papilloma. Arch Otolaryngol 82:296–300PubMedCrossRefGoogle Scholar
  22. Macbeth RG (1965) Malignant disease of the paranasal sinuses. J Laryngol Otol 79:592–612PubMedCrossRefGoogle Scholar
  23. McIvor J (1974) The radiological features of ameloblastoma. Clin Radiol 25:237–242PubMedCrossRefGoogle Scholar
  24. Malassez L (1885) Sur le rôle des débris epitheliaux paradentaires. Arch Physiol Normal Pathol (3rd series) 6:379–449Google Scholar
  25. Michaels L (1987) Ear, nose and throat histopathology. Springer, Berlin Heidelberg New YorkGoogle Scholar
  26. Mukherjee DK (1978) Choriocarcinoma of the nose. Ann Otol Rhinol Laryngol 87:257–259PubMedGoogle Scholar
  27. Nahum AM, Bailey BJ (1963) Malignant tumours metastatic to the paranasal sinuses: case report and review of literature. Laryngoscope 73:942–953PubMedCrossRefGoogle Scholar
  28. Ringertz N (1938) Pathology of malignant tumours arising in the nasal and paranasal cavities and maxilla. Acta Otolaryngol [Suppl] 27:1–390Google Scholar
  29. Salimi R (1977) Metastatic choriocarcinoma of the nasal mucosa. J Surg Oncol 9:301–305PubMedCrossRefGoogle Scholar
  30. Shaw H (1964) Clinical importance of orbital signs in cancer of the paranasal sinuses. Proc R Soc Med 57:742–747PubMedGoogle Scholar
  31. Spiro RH, Koss LG, Hajdu SI, Strong EW (1973) Tumors of minor salivary origin. Cancer 31:117–129PubMedCrossRefGoogle Scholar
  32. Ward N (1854) Follicular tumour involving nasal bones, nasal processes of superior maxillary bone and septum of nose. Removal, death from pneumonia, autopsy. Lancet II:480CrossRefGoogle Scholar
  33. Worgan D, Hooper R (1970) Malignancy in nasal papillomata. J Laryngol Otol 84:309–316PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Glyn A. S. Lloyd
    • 1
  1. 1.Royal National Throat, Nose and Ear HospitalLondonUK

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