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Diseases of the Arterial Wall pp 269–278Cite as

The Arterial Wall: Relationships Between Haemodynamic and Structural Aspects in Man

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Abstract

The relationships between the arterial wall and haemodynamic factors have been investigated many times in animal experiments. For evident methodological reasons, comparable studies are difficult to carry out in man. Many indices of cardiovascular function can be studied extensively but structural modifications of the vascular wall are more difficult to demonstrate. Autopsy observations are of little help in physiopathological terms because of the advanced nature of the lesions found. In vivo biopsies are difficult to obtain and interpret owing to the concomitant modifications in the geometry of the arterial walls. Recently, ultrasonographic techniques in man [20] have been developed and applied to the non-invasive measurement of the internal diameter of superficial peripheral arteries, and linear changes have been studied in vivo [11,21,27].

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References

  1. Berry CL, Henrichs J (1982) Morphometric investigations of hypertrophy in the arteries of DOCA hypertensive rats. J Pathol 136:85–94

    Article  PubMed  CAS  Google Scholar 

  2. Bouthier J, Benetos A, Simon A, Levenson J, Safar M (1985) Pulsed Doppler evaluation of diameter, blood velocity and blood flow of common carotid artery in sustained essential hypertension. J Cardiovasc Pharmacol 7:S99-S104

    Article  PubMed  Google Scholar 

  3. Carlier P, Rorive G (1985) Pathogenesis and reversibility of the aortic changes in experimental hypertension. J Cardiovasc Pharmacol 7:S46-S51

    Article  PubMed  CAS  Google Scholar 

  4. Chau NPH, Safar ME, London GM, Weiss YA (1979) Essential hypertension: an approach to clinical data by the use of models. Hypertension 2:87–97

    Google Scholar 

  5. Furuyama M (1962) Histometrical investigations of arteries in reference to arterial hypertension. Tokohu J Exp Med 75:388–414

    Article  Google Scholar 

  6. Folkow B (1982) Physiological aspect of primary hypertension. Physiol Rev 62:347–503

    PubMed  CAS  Google Scholar 

  7. Green JF (1977) Mechanical concepts in cardiovascular and pulmonary physiology. Lea and Febiger, Philadelphia, pp 25–54

    Google Scholar 

  8. Guyton AC (1980) Circulatory physiology III. Arterial pressure and hypertension. Saunders, Philadelphia pp 293–306

    Google Scholar 

  9. Korner PL, Shaw J, Uther B, West MJ, McRitchie RJ, Richards JG (1973) Autonomic and non-autonomic circulatory components in essential hypertension in man. Circulation 68:107–117

    Google Scholar 

  10. Labouret G, Achimastos A, Benetos A, Safar M, Housset E (1983) L’hypertension artérielle systolique des amputés traumatiques. Presse Med 21:393–400

    Google Scholar 

  11. Levenson JA, Peronneau PP, Simon ACH, Safar ME (1981) Pulsed Doppler: determination of diameter, blood flow velocity and volume flow of brachial artery in man. Cardiovasc Res 15:164–170

    Article  PubMed  CAS  Google Scholar 

  12. Levenson JA, Simon ACH, Safar ME, Fiessinger JN, Housset EM (1982) Systolic hypertension in arteriosclerosis obliterans of the lower limbs. Clin Exp Hypertens [A] 4:1059–1072

    CAS  Google Scholar 

  13. Levenson JA, Simon ACH, Maarek BE, Gitelman GJ, Fiessinger JN, Safar ME (1985) Regional compliance of brachial artery and saline infusion in patients with arteriosclerosis obliterans. Arteriosclerosis 5:80–87

    Article  PubMed  CAS  Google Scholar 

  14. Levy BI, Benessiano J, Poitevin P, Lubin L, Safar ME (1985) Systemic arterial compliance in normotensive and hypertensive rats. J Cardiovasc Pharmacol [Suppl 2] 7:22–27

    Google Scholar 

  15. London GM, Levenson JA, Safar ME, Simon ACH, Guerin AP, Payen D (1983) Hemodynamic effects of head-down tilt in normal subjects and sustained hypertensive patients. Am J Physiol 245:H195-H202

    Google Scholar 

  16. Milnor WR (1982) Hemodynamics. Williams and Wilkins, London, pp 56–91, 189–231

    Google Scholar 

  17. Mulvany MJ (1984) Pathophysiology of vascular smooth muscle in hypertension. J Hypertens [Suppl 3] 2:413–420

    Google Scholar 

  18. O’Rourke MF (1982) Arterial function in health and disease. Churchill Livingstone, Edinburgh, pp 53–66, 153–169, 196–252

    Google Scholar 

  19. Owens GK, Rabinovitch PS, Schwartz SM (1982) Smooth muscle cell hypertrophy versus hyperplasia in hypertension. Proc Natl Acad Sci USA 78:7759–7765

    Article  Google Scholar 

  20. Peronneau PP, Leger F (1977) Applications of pulsed Doppler systems. Echocardiology. Martinus Nijhoff, The Hague, pp 223–232

    Google Scholar 

  21. Safar ME, Peronneau PP, Levenson JA, Totomoukouo JA, Simon ACH (1981) Pulsed Doppler: diameter, blood flow velocity and volumic flow of the brachial artery in sustained essential hypertension. Circulation 63:393–400

    Article  PubMed  CAS  Google Scholar 

  22. Safar ME, Simon ACH, Levenson JA, Cazor JL (1983) Hemodynamic effect of Diltiazem in hypertension. Circ Res [Suppl I] 52:169–173

    Google Scholar 

  23. Safar ME, Bouthier JA, Levenson JA, Simon AC (1983) Peripheral large arteries and the response to antihypertensive treatment. Hypertension [Suppl III] 5:63–68

    Google Scholar 

  24. Safar ME, Simon ACH, Levenson JA (1984) Structural changes of large arteries in sustained essential hypertension. Hypertension [Suppl III] 6:117–121

    Google Scholar 

  25. Simon ACH, Safar ME, Levenson JA, London GM, Levy BI, Chau NPh (1979) An evaluation of large arteries compliance in man. Am J Physiol 237:H550-H554

    PubMed  CAS  Google Scholar 

  26. Simon ACH, Safar ME, Levenson JA, Kheder AD, Levy BI (1979) Systolic hypertension: hemodynamic mechanisms and choice of antihypertensive treatment. Am J Cardiol 44:505–511

    Article  PubMed  CAS  Google Scholar 

  27. Simon ACH, Laurent S, Levenson JA, Bouthier J, Safar ME (1983) Estimation of forearm arterial compliance in normal and hypertensive men from simultaneous pressure and Doppler flow measurements. Cardiovasc Res 17:331–338

    Article  PubMed  CAS  Google Scholar 

  28. Sivertsson R (1970) The hemodynamic importance of structural vascular changes in essential hypertension. Acta Physiol Scand [Suppl] 343:1–56

    CAS  Google Scholar 

  29. Suwa N, Takahashi T (1971) Morphological and morphometrical analysis of circulation in hypertension and ischemic kidney. Urban and Schwarzenberg, Berlin

    Google Scholar 

  30. Tarazi RC, Fouad FM (1984) Reversal of cardiac hypertrophy in humans. Hypertension [Suppl III] 6:140–146

    Google Scholar 

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Authors
  1. M. Safar
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  2. A. Simon
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  3. J. Levenson
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Editor information

Editors and Affiliations

  1. Service d’Anatomie Pathologique et Unité de Recherche sur la Pathologie Rénale et Vasculaire, INSERM U28, Paris, France

    Jean-Pierre Camilleri (Professeur) (Professeur)

  2. Department of Morbid Anatomy, Institute of Pathology, The London Hospital, Whitechapel, London, E1 1BB, UK

    Colin L. Berry (Professor) (Professor)

  3. Service de Médecine Interne et de Pathologie Vasculaire, Hôpital Broussais, Paris, France

    Jean-Noël Fiessinger (Professeur) (Professeur)

  4. Service de Néphrologie et Unité de Recherche sur la Pathologie Rénale et Vasculaire, INSERM U28, Hôpital Broussais, Paris, France

    Jean Bariéty (Professeur) (Professeur)

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© 1989 Springer-Verlag Berlin Heidelberg

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Safar, M., Simon, A., Levenson, J. (1989). The Arterial Wall: Relationships Between Haemodynamic and Structural Aspects in Man. In: Camilleri, JP., Berry, C.L., Fiessinger, JN., Bariéty, J. (eds) Diseases of the Arterial Wall. Springer, London. https://doi.org/10.1007/978-1-4471-1464-2_18

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  • DOI: https://doi.org/10.1007/978-1-4471-1464-2_18

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1466-6

  • Online ISBN: 978-1-4471-1464-2

  • eBook Packages: Springer Book Archive

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