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Mesothelium as a Non-thrombogenic Surface

  • Carol M. Blow
Part of the The Bloomsbury Series in Clinical Science book series (BLOOMSBURY)

Abstract

The mesothelial cell has many features in common with the endothelial cell, both in structure and in function. It is in these similarities that our interests lie—in the potential for using mesothelium as a substitute for endothelium.

Keywords

Mesothelial Cell Dacron Graft Peritoneal Mesothelial Cell Fibrin Plate Arterial Prosthesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Andrews PM, Porter KP (1973) The ultrastructural morphology and possible functional significance of mesothelial microvilli. Anat Rec 177:409–426.PubMedCrossRefGoogle Scholar
  2. Baradi AF, Hope J (1964) Observations on ultrastructure of rabbit mesothelium. Exp Cell Res 34:33–44.PubMedCrossRefGoogle Scholar
  3. Casley-Smith JR (1969) The dimensions and numbers of small vesicles in cells, endothelial and mesothelial, and the significance of these for endothelial permeability. J Microsc 90:251–269.PubMedCrossRefGoogle Scholar
  4. Clarke JMF, Pittilo RM, Machin SJ, Woolf N (1984a) A study of the possible role of mesothelium as a surface for flowing blood. Thromb Haemost 51(1):57–60.PubMedGoogle Scholar
  5. Clarke JMF, Pittilo RM, Nicholson LJ, Woolf N, Marston A (1984b) Seeding Dacron arterial prostheses with peritoneal mesothelial cells: a preliminary morphological study. Br J Surg 71:492–494.PubMedCrossRefGoogle Scholar
  6. Coene MC, Solheid C, Claeys M, Herman AG (1981) Prostaglandin production by cultured mesothelial cells. Arch Int Pharmacodyn 249:316–318.PubMedGoogle Scholar
  7. Dobbie JW, Zaki M, Wilson L (1981) Ultrastructural studies on the peritoneum with special reference to chronic ambulatory peritoneal dialysis. Scott Med J 26:213–223.PubMedGoogle Scholar
  8. Ducibella T, Ukena T, Karnovsky M, Anderson E (1977) Changes in cell surface and cortical cytoplasmic organisation during early embryogenesis of the preimplantation mouse embryo. J Cell Biol 74:153–167.PubMedCrossRefGoogle Scholar
  9. Fujimoto S, Yamamoto K, Takeshige Y (1975) Electron microscopy of endothelial microvilli of large arteries. Anat Rec 183:259–266.PubMedCrossRefGoogle Scholar
  10. Fukata H (1963) Electron microscopic study on normal rat peritoneal mesothelium and its changes in absorption of particulate iron dextran complex. Acta Pathol Japon 13:309–325.Google Scholar
  11. Graham LM, Vinter DW, Ford JW, Khan RH, Burkel WE, Stanley JC (1980) Endothelial seeding of prosthetic vascular grafts. Arch Surg 115:929–933.PubMedGoogle Scholar
  12. Herman AG, Claeys M, Moncada S, Vane JR (1979) Biosynthesis of prostacyclin (PGI2) and 12-L-hyd-roxy-5, 8, 10, 14-eicosatetraenoic acid (HETE) by pericardium, pleura, peritoneum and aorta of the rabbit. Prostaglandins 18:439–444.PubMedCrossRefGoogle Scholar
  13. Herring MB, Dilley R, Jersild RA, Boxer L, Gardner A, Glover J (1979) Seeding arterial prostheses with vascular endothelium. Ann Surg 190:84–91.PubMedCrossRefGoogle Scholar
  14. Madison LD, Bergstrom-Porter B, Torres R, Shelton E (1979) Regulation of the surface topography of mouse peritoneal mesothelial cells. J Cell Biol 82:783–797.PubMedCrossRefGoogle Scholar
  15. Moncada S, Gryglewski R, Bunting S, Vane JR (1976) An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature 263:663.PubMedCrossRefGoogle Scholar
  16. Nicholson LJ, Clarke JMF, Pittilo RM, Machin SJ, Woolf N (1984) The mesothelial cell as a non-throm-bogenic surface. Thromb Haemost 52(2):102–104.PubMedGoogle Scholar
  17. Pittilo RM, Mackie IJ, Rowles PM, Machin SJ, Woolf N (1982) Effects of cigarette smoking on the ultra-structure of the rat thoracic aorta and its ability to produce prostacyclin. Thromb Haemost 48(2):173–176.PubMedGoogle Scholar
  18. Pittilo RM, Clarke JMF, Harris D, Mackie IJ, Rowles PM, Machin SJ, Woolf N (1984a) Cigarette smoking and platelet adhesion. Br J Haematol 58:627–632.PubMedCrossRefGoogle Scholar
  19. Pittilo RM, Nicholson LJ, Clarke JMF, Blow CM, Woolf N (1984b) Cigarette smoke-induced injury of peritoneal mesothelial cells. Br J Exp Pathol 65:365–370.Google Scholar
  20. Pittilo RM, Bull HA, Blow CM, Woolf N, Machin SJ (1985) Mesothelial cell seeding of Dacron arterial prostheses. Lancet I:347–348.CrossRefGoogle Scholar
  21. Porter JM, McGregor FH, Mullen DC, Silver D (1969) Fibrinolytic activity of mesothelial surfaces. Surg Forum 20:80–82.PubMedGoogle Scholar
  22. Pugatch EMJ, Foster EA, Macfarlane DE, Poole JCF (1970) The extraction and separation of activators and inhibitors of fibrinolysis from bovine endothelium and mesothelium. Br J Haematol 18:669–681.PubMedCrossRefGoogle Scholar
  23. Schwarz W (1974) The surface film on the mesothelium of the serous membranes of the rat. Z Zeilforsch 147:595–597.CrossRefGoogle Scholar
  24. Shirahama T, Cohen AS (1972) The role of mucopolysaccharides in vesicle architecture and endothelial transport. J Cell Biol 52:198–206.PubMedCrossRefGoogle Scholar
  25. Simionescu M, Simionescu N (1977) Organisation of cell junctions in the peritoneal mesothelium. J Cell Biol 74:98–110.PubMedCrossRefGoogle Scholar
  26. Whitaker D, Papadimitriou JM, Walters MN-I (1982) The mesothelium: its fibrinolytic properties. J Pathol 136:291–299.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Carol M. Blow

There are no affiliations available

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