The Role of Fluid Replacement in Acute Endotoxin Shock

  • U. Kreimeier
  • Zh. Yang
  • K. Messmer
Part of the Current Concepts in Critical Care book series (CRITICAL CARE)


While it is generally agreed that volume replacement is one of the most important aspects of the treatment of septic shock, the choice of the volume substitute continues to be the subject of controversy. In this chapter we shall review some of the more relevant literature concerning volume replacement and the pathophysiology of septic shock. In addition, new aspects of hyperdynamic endotoxaemia evolving from a recently developed experimental model in the pig are discussed with respect to the effects of volume substitution using either Ringer’s lactate or dextran 60.


Septic Shock Pulmonary Capillary Wedge Pressure Pulmonary Arterial Pressure Total Peripheral Resistance Adult Respiratory Distress Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • U. Kreimeier
  • Zh. Yang
  • K. Messmer

There are no affiliations available

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