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Sweetness pp 33-47 | Cite as

Is Sweetness Unitary? An Evaluation of the Evidence for Multiple Sweets

  • Linda M. Bartoshuk
Part of the ILSI Human Nutrition Reviews book series (ILSI HUMAN)

Abstract

The nineteenth century concept of sweet as a “basic” taste implied that sweetness was psychologically unitary. But if sweetness is unitary, then why don’t all sweeteners taste alike? One possible answer is that various sweetener molecules can be discriminated from one another by non-sweet attributes (e.g., bitterness, slow onset, persistence of sweetness, etc.). Another possible answer is that sweetness itself varies across sweeteners.

Keywords

Squirrel Monkey Sweet Taste Psychophysical Function Receptor Mechanism Gymnemic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Andersson B, Landgren S, Olsson L (1950) The sweet taste fibres of the dog. Acta Physiol Scand 21:105–119PubMedCrossRefGoogle Scholar
  2. Bartoshuk LM (1968) Water taste in man. Percept Psychophys 3: 69–72CrossRefGoogle Scholar
  3. Bartoshuk LM (1975) Taste mixtures: Is mixture suppression related to compression? Physiol Behav 14: 643–649PubMedCrossRefGoogle Scholar
  4. Bartoshuk LM (1979) Bitter taste of saccharin: related to the genetic ability to taste the bitter substance 6-n-propylthiouracil (PROP). Science 205: 934–935PubMedCrossRefGoogle Scholar
  5. Bartoshuk LM, Cleveland CT (1977) Mixtures of substances with similar tastes: a test of a new model of taste mixture interactions. Sen Proc 1:177–186Google Scholar
  6. Bartoshuk LM, Dateo GP, Vandenbelt DJ, Buttrick RL, Long L (1969) Effects of Gymnema sylvestre and Synsepalum dulcificum on taste in man. In: Pfaffmann C (ed) Taste and olfaction. III: Rockefeller Press, New York, pp 436–444Google Scholar
  7. Bartoshuk LM, Lee CH, Scarpellino R (1972) Sweet taste of water induced by artichoke (Cynara scolymus). Science 178: 988–990PubMedCrossRefGoogle Scholar
  8. Bartoshuk LM, Rifkin B, Marks LE, Bars P (1986) Taste and aging. J Gerontol 41: 51–57PubMedGoogle Scholar
  9. Beidler L (1983) Multiple receptor sites (abstr). Chem Senses 8: 244Google Scholar
  10. Blakeslee AF (1935) A dinner demonstration of threshold differences in taste and smell. Science 81: 504–507PubMedCrossRefGoogle Scholar
  11. DeSimone JA, Heck GL, Bartoshuk LM (1980) Surface active taste modifiers: a comparison of the physical and psychophysical properties of gymnemic acid and sodium lauryl sulfate. Chem Senses 5: 317–330CrossRefGoogle Scholar
  12. Faull JR, Halpern BP (1971) Reduction of sucrose preference in the hamster by gymnemic acid. Physiol Behav 7: 903–907PubMedCrossRefGoogle Scholar
  13. Faurion A, Saito S, MacLeod P (1980) Sweet taste involves several distinct receptor mechanisms. Chem Senses 5: 107–121CrossRefGoogle Scholar
  14. Fischer R (1971) Gustatory, behavioral and pharmacological manifestations of chemoreception in man. In: Ohloff G, Thomas AF (eds) Gustation and olfaction. Academic Press, New York, pp 187–237Google Scholar
  15. Fisher GL, Pfaffmann C, Brown E (1965) Dulcin and saccharin taste in squirrel monkeys, rats and men. Science 150: 506–507PubMedCrossRefGoogle Scholar
  16. Frank M (1974) The classification of mammalian afferent taste nerve fibers. Chem Senses Flav 1:53–60CrossRefGoogle Scholar
  17. Gent JF, Bartoshuk LM (1983) Sweetness of sucrose, neohesperidine dihydrochalcone, and saccharin is related to genetic ability to taste the bitter substance 6-n-propylthiouracil. Chem Senses 7: 265–272CrossRefGoogle Scholar
  18. Glaser D, Hellekant G, Brouwer JN, Van der Wel H (1978) The taste responses in primates to the proteins thaumatin and monellin and their phylogenetic implications. Folia Primatol 29: 56–63PubMedCrossRefGoogle Scholar
  19. Glaser D, Hellekant G, Brouwer JN, Van der Wel H (1984) Effects of gymnemic acid on sweet taste perception in primates. Chem Senses 8: 367–374CrossRefGoogle Scholar
  20. Hahn H (1949) Beiträge zur Reizphysiologie. Scherer, Heidelberg Harris H, Kalmus H (1949) The measurement of taste sensitivity to phenylthiourea (P.T.C.). Ann Eugen 15: 24–31CrossRefGoogle Scholar
  21. Hellekant G, Roberts TW (1983) Study of the effect of gymnemic acid on taste in hamster. Chem Senses 8:195–202CrossRefGoogle Scholar
  22. Hellekant G, Hagstrom EC, Kasahara Y, Zotterman Y (1974) On the gustatory effects of miraculin and gymnemic acid in the monkey. Chem Senses Flav 1:137–145CrossRefGoogle Scholar
  23. Hellekant G, Glaser D, Brouwer J, Van der Wel H (1981) Gustatory responses in three prosimian and two simian primate species (Tupapia glis, Nycticebus, Galago senegalensis, Callithrix jacchus jacchus and Saguinus midas niger) to six sweeteners and miraculin and their phylogenetic implications. Chem Senses 6:165–173CrossRefGoogle Scholar
  24. Hiji Y (1975) Selective elimination of taste responses to sugars by proteolytic enzymes. Nature 256: 427–429PubMedCrossRefGoogle Scholar
  25. Hiji Y, Ito J (1977) Removal of sweetness by proteases and its recovery mechanism in rat taste cells. Comp Biochem Physiol 58:109–113CrossRefGoogle Scholar
  26. Jakinovich W (1981) Stimulation of the gerbil’s gustatory receptors by artificial sweeteners. Brain Res 210: 69–81PubMedCrossRefGoogle Scholar
  27. Jakinovich W (1983) Methyl 4,6-dichloro-4,6-dideoxy-αD-galactopyranoside: an inhibitor of sweet taste responses in gerbils. Science 219: 408–410PubMedCrossRefGoogle Scholar
  28. Jakinovich W, Vlahopoulos V (1984) Inhibition of the gerbil’s electrophysiological sucrose taste response by para-nitro-phenyl-α-D-glucopyranoside and chloramphenicol. Paper presented at the 6th Annual Meeting of the Association for Chemoreception Sciences, Sarasota, FloridaGoogle Scholar
  29. Kroeze JHA, Bartoshuk LM (1985) Bittemess suppression as revealed by split-tongue taste stimulation in humans. Physiol Behav 35: 779–783PubMedCrossRefGoogle Scholar
  30. Kurihara K (1971) Taste modifiers. In: Beidler LM (ed) Handbook of sensory physiology, vol IV. Chemical senses, part 2, Taste. Springer, New York Berlin Heidelberg, pp 363–378Google Scholar
  31. Kurihara K, Kurihara Y, Beidler LM (1979) Isolation and mechanism of taste modifiers; taste-modifying protein and gymnemic acids. In: Pfaffmann C (ed) Olfaction and taste III. Pergamon Press, New York, pp 451–469Google Scholar
  32. Lawless HT (1979) Evidence for neural inhibition in bittersweet taste mixtures. J Comp Physiol Psychol 93: 538–547PubMedCrossRefGoogle Scholar
  33. Lawless HT, Stevens DA (1983) Cross adaptation of sucrose and intensive sweeteners. Chem Senses 7: 309–315CrossRefGoogle Scholar
  34. McBurney DH (1972) Gustatory cross adaptation between sweet-tasting compounds. Percept Psychophys 11: 225–227CrossRefGoogle Scholar
  35. McBurney DH, Bartoshuk LM (1973) Interactions between stimuli with different taste qualities. Physiol Behav 10:1101–1106PubMedCrossRefGoogle Scholar
  36. McBurney DH, Gent JF (1978) Taste of methyl-a-D-mannopyranoside: effects of cross adaptation and Gymnema sylvestre. Chem Senses Flav 3: 45–50CrossRefGoogle Scholar
  37. McBurney DH, Smith DV, Shick TR (1972) Gustatory cross adaptation: sourness and bitterness. Percept Psychophys 11: 228–232CrossRefGoogle Scholar
  38. Meiselman HL (1975) Effect of response task on taste adaptation. Percept Psychophys 17: 591–595CrossRefGoogle Scholar
  39. Meiselman HL, DuBose CN (1976) Failure of instructional set to affect completeness of taste adaptation. Percept Psychophys 19: 226–230CrossRefGoogle Scholar
  40. Pfaffmann C (1969) Taste preference and reinforcement. In: Tapp JT (ed) Reinforcement and behavior. Academic Press, New York, pp 215–241Google Scholar
  41. Pfaffmann C, Frank M, Bartoshuk LM, Snell TC (1976) Coding gustatory information in the squirrel monkey chorda tympani. In: Sprague JM, Epstein A (eds) Progress in physiological psychology, vol 6. Academic Press, New York, pp 1–27Google Scholar
  42. Schiffman SS, Cahn H, Lindley MG (1981a) Multiple receptor sites mediate sweetness: evidence from cross adaptation. Pharm Biochem Behav 15: 377–388CrossRefGoogle Scholar
  43. Schiffman SS, Lindley MG, Clark TB, Makino C (1981b) Molecular mechanism of sweet taste: relationship of hydrogen bonding to taste sensitivity for both young and elderly. Neurobiol Aging 2:173–185PubMedCrossRefGoogle Scholar
  44. Settle RG (1981) Suprathreshold glucose and fructose sensitivity in individuals with different family histories of non-insulin-dependent diabetes mellitus. Chem Senses 6: 435–443CrossRefGoogle Scholar
  45. Shallenberger RS, Acree TE (1967) Molecular theory of sweet taste. Nature 216: 480–482PubMedCrossRefGoogle Scholar
  46. Smith DV, McBurney DH (1969) Gustatory cross adaptation: does a single mechanism code the salty taste? J Exp Psychol 80:101–105PubMedCrossRefGoogle Scholar
  47. Van der Wel H (1972) Thaumatin, the sweet-tasting protein from Thaumatococcus Daniellii Benth. In: Schneider D (ed) Olfaction and taste. Wissenschaftliche Verlagsgesellschaft, Stuttgart, pp 226–233Google Scholar
  48. Van der Wel H, Arvidson K (1978) Qualitative psychological studies on the gustatory effects of the sweet tasting proteins thaumatin and monellin. Chem Senses Flav 3: 291–297CrossRefGoogle Scholar
  49. Vlahopoulus V, Jakinovich W (1985) Inhibition of the gerbil’s electrophysical sweetener response by methyl 4,6-dichloro-4,6-dideoxy α-D-galactopyranoside, p-nitrophenyl α-D-glucopyranoside and chloramphenicol. Chem Senses 10: 432Google Scholar
  50. Warren RM, Pfaffmann C (1959) Inhibition of the sweet taste by Gymnema sylvestre. J Appl Physiol 14: 40–42PubMedGoogle Scholar
  51. Yamamoto T, Kato T, Kawamura Y, Yoshida M (1984) Gustatory reaction time to various sweeteners. Chem Senses 9: 79Google Scholar
  52. Zawalich WS (1973) Depression of gustatory sweet response by alloxan. Comp. Biochem Physiol 44A: 903–909CrossRefGoogle Scholar

References

  1. Blakeslee AF (1935) A dinner demonstration of threshold differences in taste and smell. Science 81: 504–507PubMedCrossRefGoogle Scholar
  2. Hahn H (1949) Beiträge zur Reizphysiologie. Scherer, HeidelbergGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • Linda M. Bartoshuk

There are no affiliations available

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