Secondary Carcinoma

  • T. H. Moss


Carcinomas are the most common type of secondary tumour found in the central nervous system, and although they may be the result of direct spread from a local primary site such as the mastoid antrum, they are most often distant metastases spread by a haematogenous route. In either case, the ultrastructural features of these secondary deposits are identical to those of carcinomas elsewhere in the body, and the appearances vary widely depending on the site of the primary tumour and the degree of differentiation in the metastases. In most instances, however, a number of basic features can be identified at electron microscopic level which enable secondary carcinoma deposits to be distinguished from other central nervous system tumours, including choroid plexus carcinomas (see Chapter 8).


Squamous Carcinoma Ultrastructural Feature Central Nervous System Tumour Central Nervous System Metastasis Electron Microscopic Level 
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  1. Ghadially FN (1980) Diagnosis electron microscopy of tumours. Butterworths, London, pp 51 - 77Google Scholar
  2. Trump BF, Jesudason ML, Jones RT (1978) Ultrastructural features of diseased cells: neoplasia. In: Trump BF, Jones RT (eds) Diagnostic electron microscopy, vol 1. John Wiley, New York, pp 54 - 64Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • T. H. Moss
    • 1
  1. 1.Department of NeuropathologyFrenchay HospitalBristolUK

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