Clinical Use of Intravenous Gadolinium-DTPA in Magnetic Resonance Imaging of the Central Nervous System

  • G. M. Bydder
  • H. P. Niendorf
  • I. R. Young


Following extensive pharmacological and animal studies (Weinmann and Grier 1983; Weinmann et al. 1984), clinical trials with intravenous gadolinium-DTPA (Gd-DTPA) were begun at the end of 1983 (Shorner et al. 1984). During 1984 one group in Berlin (Claussen et al. 1985; Felix et al. 1984a, b) and another in London (Carr et al. 1984a, b; Graif et al., to be published; Curati et al., to be published; Bydder et al. 1985) conducted clinical trials. During 1985 Gd-DTPA was released more widely and now over 20 groups in Europe and four in the United States are involved in clinical evaluation programmes. Gd-DTPA is the first parenteral magnetic contrast agent available for clinical use and the results of these clinical trials have been followed with considerable interest.


Contrast Agent Contrast Enhancement Comput Assist Spin Echo Acoustic Neuroma 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • G. M. Bydder
  • H. P. Niendorf
  • I. R. Young

There are no affiliations available

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