Pharmacological Management of the Neuropathic Bladder and Urethra
The demand upon physicians to treat a growing number of patients with neuropathic bladder and urethra can be traced to a variety of reasons. The improved emergency services and intensive care provided for trauma victims have resulted in an increased survival of patients, many of whom have spinal cord and peripheral nerve injury. Additionally, the increased use of newer diagnostic equipment and an increased index of suspicion for neuropathic bladder disorders have improved our ability to recognise these problems. Extensive dissemination of new information pertaining to neurogenic bladder and sphincter dysfunctions has thrust the problem into a more prominent position in modern medical practice.
KeywordsDiazepam Acetylcholine Atropine Cholinesterase Flushing
Unable to display preview. Download preview PDF.
- Cannon WB, Rosenbleuth A (1949) The supersensitivity of denervated structures. Macmillan, New YorkGoogle Scholar
- Diokno AC, Davis R, Lapides J (1975) Urecholine test for denervated bladders. Invest Urol 13: 233–235Google Scholar
- Gosling JA, Dixon JS (1979) Light and electron microscopic observations on the human external urethral sphincter. J Anat 129: 216Google Scholar
- Koff SA, Lapides, J, Piazza DH (1979) The uninhibited bladder in children: a cause for urinary obstruction, infection, and reflux. In: Hodson J, Kincaid-Smith P (eds) Reflux nephropathy. Masson Publishing, New York, pp 161–169Google Scholar
- Lapides J, Diokno AC (1976) Urine transport, storage and micturition. In: Lapides J (ed) Fundamental of urology. WB Saunders, Philadelphia, pp 190–241Google Scholar
- Lapides J, Friend CR, Ajemian EP, Reus WS (1962) Denervation supersensitivity as a test for neurogenic bladder. Surg Gynecol Obstet 114: 241–244Google Scholar
- Raz S, Bradley WE (1979) Neuromuscular dysfunction of the lower urinary tract. In: Harrison JH et a1. (eds) Urology, 4th edn. WB Saunders, Philadelphia, pp 1215–1270Google Scholar