Skip to main content
SpringerLink
Log in

Penile Cancer: Natural History and Therapy

  • Chapter
Chemotherapy and Urological Malignancy

Part of the book series: Clinical Practice in Urology ((PRACTICE UROLOG))

Abstract

Squamous cell carcinoma of the penis although uncommon in the United States and European countries is a significant world health problem. The etiology of penile cancer is unknown, but societies that practice early circumcision and enjoy socioeconomic statuses which permit proper hygiene have a distinctly lower incidence (DeKernion and Persky 1978).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abe N (1976) Simultaneous combination treatment with bleomycin and radiotherapy for the penile cancer. (Unpublished) Cited in Ichikawa 1976

    Google Scholar 

  • Allaire FJ, Thieme ET, Corst DR. (1961) Cancer chemotherapy with 5-fluorouracil alone and in combination with X-ray therapy. Cancer Chemother Rep 14: 59–75

    PubMed  CAS  Google Scholar 

  • Blum RH, Carter SK, Agre K (1973) A clinical review of bleomycin-a new antineoplastic agent. Cancer 31:903–914

    Article  PubMed  CAS  Google Scholar 

  • Bonadonna G, DeLena M, Monfanni S, Bartoli C, Bajetta E, Beretta G, Fossati-Bellani F (1972) Clinical trials with bleomycin in lymphomas and in solid tumors. Eur J Cancer 8: 205–215

    PubMed  CAS  Google Scholar 

  • Brennan MJ, Vaitkevicious VK (1960) 5-Fluorouracil in clinical cancer -experience with 155 patients. Cancer Chemother Rep 6: 8–11

    PubMed  CAS  Google Scholar 

  • Cabanas RM (1977) An approach for the treatment of penile carcinoma. Cancer 39:456–466

    Article  PubMed  CAS  Google Scholar 

  • Carson TE (1978) Verrucous carcinoma of the penis: Successful treatment with cryosurgery and topical fluorouracil therapy. Arch Dermatol 114:1546–1547

    Article  PubMed  CAS  Google Scholar 

  • Conduit T, Snider I, Owens AH (1962) Studies in the folic acid vitamins: The effects of large doses of amethopterin in patients with cancer. Cancer Res 22:706–712

    Google Scholar 

  • DeKeraion JB, Persky L (1978) Neoplastic lesions of the penis. In: Skinner D, DeKernion JB (eds) Genitourinary cancer. Saunders, Philadelphia, pp 494–508

    Google Scholar 

  • Dietrich FS (1968) Clinical trial with dihydroxybusulfan (NSC-390669) Cancer Chemother Rep 52: 603–609

    PubMed  CAS  Google Scholar 

  • Dietrich FS, Cope C, Rivers S, Krantz S, Baum G, Beck HJ, Rodensky, PL (1962) Clinical trial with alanine mustard. Cancer Chemother Rep 23:31–38

    PubMed  CAS  Google Scholar 

  • Folke E (1976) Combined treatment with bleomycin in penile carcinomas. GAN Monogr 19:231–233

    Google Scholar 

  • Hofsetter A (1978) Local laser-radiation of a penile carcinoma. Fortschr Med 96:369–371

    Google Scholar 

  • Ichikawa T (1976) Studies of bleomycin: Discovery of its clinical effect, combination treatment with bleomycin and radiotherapy, side effects, and long-term survival. GAN Mongr 19:99–113

    Google Scholar 

  • Ichikawa T (1977) Chemotherapy of penis carcinoma. In: Grundmann E, Vahlensieck W (eds) Tumors of the male genital system. Springer, Berlin, pp 140–156

    Google Scholar 

  • Ichikawa T, Nakano I, Hirokawa I (1969) Bleomycin treatment of the tumors of penis and scrotum. J Urol 102:699–707

    PubMed  CAS  Google Scholar 

  • Ichikawa T, Nakano I, Hirokawa I (1970) On bleomycin treatment in the urological field. In: Progress in antimicrobial and anti-cancer chemotherapy. Proceedings of the Sixth International Congress of Chemotherapy, vol 2. University Press, Tokyo, pp 304–308

    Google Scholar 

  • Johnston BJ (1962) Clinical effect of Coley’s toxin. 1. A controlled study. Cancer Chemother Rep 21: 19–41

    PubMed  CAS  Google Scholar 

  • Johnston BJ, Novales ET (1962) Clinical effect of Coley’s toxin. II. A seven-year study. Cancer Chemother Rep 21:43–68

    PubMed  CAS  Google Scholar 

  • Khezri AA, Dounis A, Roberts JBM (1979) Primary malignant melanoma of the penis. Two cases and a review of the literature. Br J Urol 51:147–150

    Article  PubMed  CAS  Google Scholar 

  • Luciani L (1977) Antiblastic chemotherapy and surgical management in the treatment of carcinoma of the penis. Minerva Urol 29: 273–277

    PubMed  CAS  Google Scholar 

  • Makoui C, Fishburne C (1978) Hypercalcemia in squamous cell carcinoma of the skin. JAMA 239: 1882–1883

    Article  PubMed  CAS  Google Scholar 

  • Marcial VA, Colon JF, Rojas RAM, Colon JE (1962) Carcinoma of the penis. Radiology 79:209–220

    PubMed  CAS  Google Scholar 

  • Mathe G (1970) Study of the clinical efficiency of bleomycin in human cancer. Br Med J ii: 643–645

    Google Scholar 

  • Merrin CE (1979) Treatment of genitourinary tumors with cis-dichlorodiammine platinum II. Cancer Treat Rep 63:1579–1584

    PubMed  CAS  Google Scholar 

  • Mills ED (1972) Intermittent intravenous methotrexate in the treatment of advanced epidermoid carcinoma. S Afr Med J 46:398–404

    PubMed  CAS  Google Scholar 

  • Murrel DS, Williams JL (1965) Radiotherapy in the treatment of carcinoma of the penis. Br J Urol 37: 211–218

    Article  Google Scholar 

  • Odujinrin OO, DeConti RC, Bertino JR (1975) Combination chemotherapy with cyclophosphamide (NSC-26271), cytosine arabinoside (NSC-63878) and methotrexate (NSC-740) in advanced solid tumors. Cancer Chemother Rep 59:1094–1096

    Google Scholar 

  • Ohnuma T, Holland JF, Sako K, Shedd DP (1972) Effects of combination therapy with bleomycin (NSC0125066) and dibromodulcitol (NSC-104800) on squamous cell carcinoma in man. Cancer Chemother Rep 56:652–633

    Google Scholar 

  • OrrPS, Habeshaw T, Scott R (1977) Carcinoma of the penis: A review of 42 cases. Br JUrol49; 7333–738

    Google Scholar 

  • Pointon RCS (1975) External beam therapy. Proe R Soc Med 68:779

    CAS  Google Scholar 

  • Pow-Sang J (1979) Carcinoma of the penis: Analysis of 192 consecutive cases at the Instituto Nacional de Enfermedades Neoplasicas. Int Adv Surg Oncol 2:201–221

    PubMed  CAS  Google Scholar 

  • Riveros M, Garcia R, Cabanas R (1965) Lymphadenography of the dorsal lymphatics of the penis. Cancer 20:2026–2031

    Article  Google Scholar 

  • Salaverria JC, Hope-Stone HF, Paris AMI, Molland EA, Blandy JP (1979) Conservative treatment of carcimona of the penis. Br J Urol 51:32–37

    Article  PubMed  CAS  Google Scholar 

  • Sklaroff RB, Yagoda A (1979) cis-Diamminedichloride platinum II (DDP) in the treatment of penile carcinoma. Cancer 44:1563–4565

    Article  PubMed  CAS  Google Scholar 

  • Sklaroff RB, Yagoda A (1980) Methotrexate in the treatment of penile carcinoma. Cancer 45:214–216

    Article  PubMed  CAS  Google Scholar 

  • Sklaroff RB, Yagoda A (to be published) Bleomycin in the treatment of penile carcinoma. Cancer

    Google Scholar 

  • Stephens FO (1973) Bleomycin -a new approach in cancer chemotherapy. Med J Aust 1:1277–1283

    PubMed  CAS  Google Scholar 

  • Stolinsky DC, Bogon DL, Solomon J, Bateman JR (1972) Hexamethylemelamine (NSC-13875) alone and in combination with 5-(3,3-dimethyl-triazeno) imidazole-4-carboxamide (NSC45388) in the treatment of advanced cancer. Cancer 30:654–659

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. 1275 York Ave., New York, N.Y., 10021, USA

    Alan Yagoda MD.

Authors
  1. R. B. Sklaroff
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Alan Yagoda MD.
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Division of Oncology, The Albany Medical College, Albany, New York, 12208, USA

    A. S. D. Spiers MB, BS, MD(Melb.), PhD, FRCPE, FRACP, FACP (Professor of Medicine) (Professor of Medicine)

Rights and permissions

Reprints and permissions

Copyright information

© 1982 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Sklaroff, R.B., Yagoda, A. (1982). Penile Cancer: Natural History and Therapy. In: Spiers, A.S.D. (eds) Chemotherapy and Urological Malignancy. Clinical Practice in Urology. Springer, London. https://doi.org/10.1007/978-1-4471-1332-4_8

Download citation

  • DOI: https://doi.org/10.1007/978-1-4471-1332-4_8

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1334-8

  • Online ISBN: 978-1-4471-1332-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation