Generalised Decrease in Bone Density

  • Frank Horan
  • Peter Beighton


Osteogenesis imperfecta (OI) is perhaps the commonest inherited skeletal dysplasia. Since the basic defect is an abnormality of the collagen other tissues, including the teeth, skin, tendons, ligaments, fasciae and sclerae, may also be affected.


Osteogenesis Imperfecta Intramedullary Fixation Autosomal Recessive Form Wormian Bone Massive Osteolysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


Osteogenesis Imperfecta

  1. Bailey RW, Dubow HI (1965) Experimental and clinical studies of longitudinal bone growth—utilizing a new method of internal fixation across the epiphyseal plate. J Bone Joint Surg [Am] 47:1669 Proceedings of the American Orthopaedic Association.Google Scholar
  2. Benson DR, Donaldson DH, Millar EA (1978) The spine in osteogenesis imperfecta. J Bone Joint Surg [Am] 60: 925Google Scholar
  3. Cristofaro RL, Hoek KJ, Bonnett CA, Brown JC (1979) Operative treatment of spinal deformity in O.I. Clin Orthop 139: 40PubMedGoogle Scholar
  4. Marafioti RL, Westin GW (1977) Elongating intramedullary rods in the treatment of osteogenesis imperfecta. J Bone Joint Surg [Am] 59: 467Google Scholar
  5. Moe JH, Winter RB, Bradford DS, Lonstein JE (1978) Scoliosis and other spinal deformities. Saunders, Philadelphia, p 607Google Scholar
  6. Moorefield WG Jnr., Miller GR (1980) Aftermath of osteogenesis imperfecta: the disease in adulthood. J Bone Joint Surg [Am] 62: 113Google Scholar
  7. Nichols PJR, Strange TV (1972) A method of casting severely deformed and disabled patients. Rheumatology and Physical Medicine 11: 356PubMedCrossRefGoogle Scholar
  8. Renshaw TS, Cook RS, Albright JA (1979) Scoliosis in osteogenesis imperfecta. Clin Orthop 145: 163PubMedGoogle Scholar
  9. Rodriguez RP (1976) Report of multiple osteotomies and intramedullary fixation by an extensible intramedullary device in children with osteogenesis imperfecta. Clin Orthop 116: 261Google Scholar
  10. Rosenberg E, Lang R, Boisseau V, Rojanasathit S, Avioli LV (1977) Effect of long term calcitonin therapy on the clinical course of osteogenesis imperfecta. J Clin Endocrinol Metab 44: 346PubMedCrossRefGoogle Scholar
  11. Rutkowski R, Resnick P, McMaster JH (1979) Osteosarcoma occurring in osteogenesis imperfecta. J Bone Joint Surg [Am] 61: 606Google Scholar
  12. Sillence DO, Senn A, Danks DM (1979) Genetic heterogeneity in osteogenesis imperfecta. J Med Genet 16: 101PubMedCrossRefGoogle Scholar
  13. Sofeld HA, Millar EA (1959) Fragmentation, realignment and intramedullary rod fixation of deformities of the long bones in children. A ten-year appraisal. J Bone Joint Surg [Am] 41: 1371Google Scholar

Idiopathic Osteolysis

  1. Burrows HJ, Wilson JN, Scales JT (1975) Excision of tumours of the humerus and femur, with restoration by internal prostheses. J Bone Joint Surg [Br] 57: 148Google Scholar
  2. Campbell J, Almond HGA, Johnson R (1975) Massive osteolysis of the humerus with spontaneous recovery. J Bone Joint Surg [Br] 57: 238Google Scholar
  3. Gluck J, Miller JJ (1972) Familial osteolysis of the carpal and tarsal bones. J Pediatr 81: 506PubMedCrossRefGoogle Scholar
  4. Johnson PM, McClure JG (1958) Observations on massive osteolysis Radiology 71: 28Google Scholar
  5. Sage MR, Allen PW (1974) Massive osteolysis. Report of a case. J Bone Joint Surg [Br] 56: 130Google Scholar
  6. Shurtleff DB, Sprakes RS, Clawson K, Guntheroth WG, Mottet NK (1964) Hereditary osteolysis with hypertension and nephropathy. JAMA 188: 363PubMedGoogle Scholar
  7. Torg JS, Steel HH (1968) Essential osteolysis with nephropathy: A review of the literature and case report of an unusual syndrome. J Bone Joint Surg Br 50: 1629Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • Frank Horan
    • 1
  • Peter Beighton
    • 2
  1. 1.Cuckfield HospitalCuckfield SussexEngland
  2. 2.Medical School and Groote Schuur HospitalUniversity of Cape TownCapeSouth Africa

Personalised recommendations