• Michael R. Hayden


Epidemiology is the study of the distribution and causes of health impairment in human populations. In contrast to the clinician, whose primary interest is the individual patient, the epidemiologist focuses on groups of persons. Epidemiological studies are, however, not confined to the determination of disease frequency and may incorporate an evaluation of the measures that need to be taken to improve health.


Mortality Data Morbidity Data Mixed Ancestry Affected Person Juvenile Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. Avila-Giron R (1973) Medical and social aspects of Huntington’s chorea in the state of Zulia, Venezuela. In: Barbeau A, Chase TN, Paulson GW (eds) Huntington’s chorea, 1872-1972. Raven Press, New York, pp 259 - 266Google Scholar
  2. Bickford JAR, Elisson RM (1953) High incidence of Huntington’s chorea in the Duchy of Cornwall. J Ment Sci 99: 291 - 294PubMedGoogle Scholar
  3. Bolt JM (1970) Huntington’s chorea in the west of Scotland. Br J Psychiatry 116: 259 - 270PubMedCrossRefGoogle Scholar
  4. Brewis M, Poskanzer DC, Rolland C, Miller W (1966) Neurological disease in an English city. Acta Neurol Scand [Suppl 24] 42: 1 - 89Google Scholar
  5. Brothers CRD (1949) The history and incidence of Huntington’s chorea in Tasmania. Proc R Aust Coll Physicians 4: 48 - 50Google Scholar
  6. Brothers CR (1964) Huntington’s chorea in Victoria and Tasmania. J Neurol Sci 1: 405 - 420CrossRefGoogle Scholar
  7. Bruyn GW, Baro F, Myrianthopoulos NC (1974) Centennial bibliography of Huntington’s chorea, 1872-1972. Leuven University Press and Martinus Nijhoff, Louvain and The Hague: pp 1 - 314Google Scholar
  8. Cameron D, Venters GA (1967) Some problems in Huntington’s chorea. Scott Med J 12: 152 - 156PubMedGoogle Scholar
  9. Caro A (1977) The prevalence of Huntington’s chorea in an area of East Anglia. J R Coll Gen Pract 27: 41 - 45PubMedGoogle Scholar
  10. Cendrowski W (1964) Niektore dañe o geograñi plasawicy dxiedzicznej. (Some remarks on the geography of hereditary chorea.) Neurol Neurochir Psychiatr Pol 14: 63 - 66PubMedGoogle Scholar
  11. Critchley M (1934) Huntington’s chorea and East Anglia. J State Med 42: 575 - 587Google Scholar
  12. Davenport CB, Muncey EB (1916) Huntington’s chorea in relation to heredity and eugenics. Am J Insan 73: 195 - 222Google Scholar
  13. Gudmundsson KR (1969) Prevalence and occurrence of some rare neurological diseases in Iceland. Acta Neurol Scand 45: 114 - 148PubMedCrossRefGoogle Scholar
  14. Harper PS, Tyler A, Walker DA, Newcombe RG, Davies K (1979) Huntington’s chorea: the basis for long- term prevention. Lancet II: 346 - 349Google Scholar
  15. Hayden MR (1979) Huntington’s chorea in South Africa. PhD thesis, University of Cape Town Hayden MR, MacGregor JM, Beighton PH (1980) The prevalence of Huntington’s chorea in South Africa. S Afr Med J 58: 193 - 6PubMedGoogle Scholar
  16. Hayden MR, MacGregor JM, Saffer DS, Beighton PH (1981) On the high frequency of juvenile Huntington’s chorea in South Africa. J Med Genet (in press) Heathfield KWG (1967)Google Scholar
  17. Huntington’s chorea: investigation into the prevalence of this disease in the area covered by the North East Metropolitan Regional Hospital Board. Brain 90: 203-232Google Scholar
  18. Heathfield KWG, MacKenzie ICK (1971) Huntington’s chorea in Bedfordshire. Guy’s Hosp Rep 120: 295 - 309PubMedGoogle Scholar
  19. Hogg JE, Massey EW, Schoenberg BS (1979) Mortality from Huntington’s disease in the United States. In: Chase, TN, Wexler NS, Barbeau A (eds) Advances in neurology, vol 23. Raven Press, New York, pp 27 - 35Google Scholar
  20. Husquinet H (1975) La chorée de Huntington, maladie héréditaire grave: conditions de sa disparition. Rev Med Liège 307: 228 - 232Google Scholar
  21. Kishimoto K, Nakamura M, Sotokawa Y (1957) Population genetics study of Huntington’s chorea in Japan. Annu Rep Res Inst Environ Med 9: 195 - 211Google Scholar
  22. Korenyi C, Whitter JR (1977) Huntington’s disease in New York State. New York J Med 771: 44 - 45Google Scholar
  23. Kurland LT (1958) Descriptive epidemiology of selected neurologic and myopathic disorders with particular reference to a survey in Rochester, Minnesota. J Chron Dis 8: 378 - 418PubMedCrossRefGoogle Scholar
  24. Kurtzke JF (1979) Huntington’s disease: mortality and morbidity data from outside the United States. In: Chase TN, Wexler NS, Barbeau A (eds) Advances in neurology, vol 23. Raven Press, New York, pp 13 - 25Google Scholar
  25. Kurtzke JF, Anderson VE, Beebe GW, Elston RC, Higgins I, Hogg J, Kurland L, Muenter M, Myrianthopoulos N, Reed TE, Schoenberg B, Schull WJ, Li CC (1977) Report of workgroup on epidemiology, biostatistics and population genetics. In: Commission for the Control of Huntington’s Disease and its Consequences vol III/1. DHEW publication (NIH) 718-1503. US Government Printing Office, Washington, DC, pp 133 - 236Google Scholar
  26. Leger JM, Ranouil R, Vallat JN (1974) Huntington’s chorea in Limousin: statistical and clinical study. Rev Med Limoges 5: 147 - 153Google Scholar
  27. Lyon RL (1962) Huntington’s chorea in the Moray Firth area. Br Med J 1: 1301 - 1306PubMedCrossRefGoogle Scholar
  28. Mattsson B (1974) Clinical, genetic and pharmacological studies in Huntington’s chorea. UMEA University Medical Dissertations 7. UMEA, Sweden, pp 21 - 51Google Scholar
  29. Minski L, Guttmann E (1938) Huntington’s chorea: study of 34 families. J Ment Sei 84: 21 - 96Google Scholar
  30. Myrianthopoulos NC (1973) Huntington’s chorea: the genetic problem five years later. In: Barbeau A, Chase TN, Paulson GW (eds) Huntington’s chorea, 1872-1972. Raven Press, New York, pp 150 - 152Google Scholar
  31. Oliver JE (1970) Huntington’s chorea in Northamptonshire. Br J Psychiatry 166: 241 - 253CrossRefGoogle Scholar
  32. Panse F (1942) Die Erbchorea: eine klinische-genetische Studie. Samml Psychiatr Neurol Einzeldarst 18. Thieme, LeipzigGoogle Scholar
  33. Parker N (1958) Observations on Huntington’s chorea based on a Queensland survey. Med J Aust I: 251 - 259Google Scholar
  34. Pearson JS, Petersen MC, Lazarte JA, Blodgett HE, Kley IB (1955) An educational approach to the social problem of Huntington’s chorea. Proc Mayo Clin 30: 349 - 357Google Scholar
  35. Pleydell MJ (1954) Huntington’s chorea in Northamptonshire. Br Med J ii: 1121 - 1128Google Scholar
  36. Pleydell MJ (1955) Huntington’s chorea in Northamptonshire. Br Med J ii: 889Google Scholar
  37. Reed TE, Chandler JH, Hughes EM, Davidson RT (1958) Huntington’s chorea in Michigan: demography and genetics. Am J Hum Genet 10: 201 - 225PubMedGoogle Scholar
  38. Reid JJ (1960) Huntington’s chorea in Northamptonshire. Br Med J ii: 650Google Scholar
  39. Scoones T (1980) Huntington’s chorea. Office of Health Economics Publication 67. OHE, London, pp 1 - 35Google Scholar
  40. Shokeir MH (1975) Investigations on Huntington’s disease in the Canadian prairies. II. Fecundity and fitness. Clin Genet 7: 349 - 353PubMedCrossRefGoogle Scholar
  41. Sjogren T (1936) Vererbungsmedizinische Untersuchungen über Huntington’s Chorea in einer schwedischen Bauernpopulation. Z Menschl Vererb-Konstit-Lehre 19: 131 - 165Google Scholar
  42. Spillane J, Phillips R (1937) Huntington’s chorea in South Wales. Q J Med 6: 403 - 423Google Scholar
  43. Stevens DL (1976) Huntington’s chorea: a demographic, genetic and clinical study. MD thesis, University of London, pp 1 - 338Google Scholar
  44. Wallace DC (1972) Huntington’s chorea in Queensland: a not uncommon disease. Med J Aust II: 1275 - 1277Google Scholar
  45. Wasserman HP (1974) Ethnic pigmentation: historical, physiological and clinical aspects. Excerpta Medica, Amsterdam, pp 254 - 255Google Scholar
  46. Wendt GG, Drohm D (1972) Krankheitsdauer und Lebenserwartung bei der Huntingtonschen Chorea. Arch Psychiatr Nervenkr 201: 298 - 312CrossRefGoogle Scholar
  47. Zolliker A (1949) Die Chorea Huntington in der Schweiz. Eine Thurgauer Sippe mit Chorea Huntington. Schweiz Arch Neurol Psychiatr 64: 448 - 457Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1981

Authors and Affiliations

  • Michael R. Hayden
    • 1
  1. 1.Division of Clinical GeneticsChildren’s Hospital Medical CenterBostonUSA

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