Under the title ‘A case of unusual bone development,’ a Connecticut orthopaedic surgeon, Edwin
Pyle (1931), reported a healthy 5-year-old boy in whom the mild clinical feature of knock-knees contrasted with gross under-modelling of the metaphyses of the tubular bones. Bakwin and Krida (1937) restudied this patient, together with his affected younger sister, and termed the condition ‘familial metaphyseal dysplasia.’ Subsequently, Hermel et al. (1953), Komins (1954), and Feld et al. (1954) employed the same designation in descriptions of pairs of affected siblings who presented in adulthood.
- Affected Sibling
- Tubular Bone
- Semantic Confusion
- Metaphyseal Dysplasia
- Sclerosing Bone Dysplasia
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