Magnetic Resonance Imaging of Patients with Isolated Idiopathic Optic Neuritis, Brainstem Syndromes and Myelopathy

  • David H. Miller


In about 90% of patients with multiple sclerosis (MS), the initial clinical event is an acute and usually reversible monosymptomatic episode of central nervous system dysfunction (Matthews 1990). In most instances, the symptoms and signs indicate the presence of a lesion in either the spinal cord (about 50% of cases), optic nerves (25%) or brainstem (15%). However, not all patients presenting with such syndromes go on to develop further neurologic events disseminated in time and space that allow the diagnosis of MS (Poser et al. 1983). Indeed, such syndromes can sometimes be a manifestation of the monophasic demyelinating disorder, acute disseminated encephalomyelitis (ADEM), or they may be due to a focal structural lesion for which there is an effective treatment.


Multiple Sclerosis Expand Disability Status Scale Optic Neuritis Lesion Load Definite Multiple Sclerosis 
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© Springer-Verlag London Limited 1996

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  • David H. Miller

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