• Peter Beighton
  • Greta Beighton


WERNICKE disease, or encephalopathy, comprises mental confusion, paralysis of the external ocular muscles, nystagmus and ataxia. Although associated with alcoholism, thiamine deficiency in genetically predisposed persons is now regarded as the major determinant of the condition.


Medulla Oblongata Thiamine Deficiency Mental Confusion Petechial Haemorrhage Thiamine Pyrophosphate 
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Copyright information

© Springer-Verlag London Limited 1997

Authors and Affiliations

  • Peter Beighton
    • 1
  • Greta Beighton
    • 1
  1. 1.Department of Human GeneticsUniversity of Cape Town Medical SchoolSouth Africa

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