• Peter Beighton
  • Greta Beighton


VAN DER HOEVE syndrome comprises brittle bones, blue sclerae and deafness. The condition is now generally known as osteogenesis imperfecta tarda, or OI type I.


Osteogenesis Imperfecta Road Traffic Accident Competent Linguist Honorary Degree Skeletal Fragility 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Adair-Dighton CA (1912) Four generations of blue sclerotics. Ophthalmoscope 10:188–189Google Scholar
  2. Eddowes A (1900) Dark sclerotics and fragilitas ossium. Br Med J 2: 222Google Scholar
  3. Ekman OJ (1788) Dissertatw medica. Descriptionem et casus aliqot osteomalaciae sistens. Uppsala, SwedenGoogle Scholar
  4. Lobstein JG (1835) Lehrbuch der pathologischen Anatomie. Stuttgart, p. 179 Obituary (1952) Br J Ophthal 36: 399–400Google Scholar
  5. Spurway J (1896) Hereditary tendency to fracture. Br Med J 2: 844PubMedCrossRefGoogle Scholar
  6. van der Hoeve J, de Kleyn A (1918) Blaue Sclerae, Knochenbruchigkeit und Schwerhörigkeit. Graefes Arch Ophth 95: 81–93CrossRefGoogle Scholar
  7. Vrolik W (1844–1849) Tabulae ad illustrandam embryogenesim hominis et mammalium, tarn naturalem quam abnormem. AmstelodamiGoogle Scholar

Copyright information

© Springer-Verlag London Limited 1997

Authors and Affiliations

  • Peter Beighton
    • 1
  • Greta Beighton
    • 1
  1. 1.Department of Human GeneticsUniversity of Cape Town Medical SchoolSouth Africa

Personalised recommendations