The tissue of the spinal cord is similar to that of the brain and is made up of two main types consisting of the highly specialized neurones (nerve cells) with their processes, and the neuroglial cells (Lantos 1990a). Both of these are of neuroectodermal origin in contrast to the second main type of tissue which has an origin in mesoderm and comprises the meninges, the blood vessels and their supporting connective tissue and microglia. Whereas some of the diseases affecting the spinal cord are similar to those seen in other organs, e.g. inflammation, vascular disease and tumours, others are primarily diseases of spinal neurones affecting their cell body, axons and myelin sheaths. Therefore, it follows that because the constituent cells of the spinal cord are similar to those found elsewhere in the nervous system, the disease processes and the tissue reaction in response to them are similar to those found elsewhere in the brain (Hughes 1978; Esiri and Oppenheimer 1989; Lantos 1990b). However, the prevalence of the various disease processes in the spinal cord differs from that found elsewhere in the brain.
KeywordsLymphoma Dementia Tuberculosis Retina Neurol
Unable to display preview. Download preview PDF.
- Allen IV (1985) Demyelinating diseases. In: Adam JH, Corsellis JAN, Duchen LW (eds) Greenfield’s neuropathology, 4th edn. Edward Arnold, London, pp 338–384Google Scholar
- Esiri MM, Oppenheimer DR (1989) Histology. In: Diagnostic neuropathology, Blackwell Scientific Publishers, Oxford, pp 46–66Google Scholar
- Henson RA, Urich H (1982) Cancer and the nervous system. The neurological manifestations of systemic malignant diseases. Blackwell Scientific, OxfordGoogle Scholar
- Hughes JT (1978) Introduction. In: Pathology of the spinal cord, Lloyd-Luke, London, pp 1–16Google Scholar
- Hughes JT (1992) Disorders of the spine and spinal cord. In: Adams JH, Duchen LW (eds) Greenfield’s neuropathology, 5th edn. London, Edward Arnold, pp 1083–1115Google Scholar
- Lantos PL (1990a) Cytology of the normal central nervous system. In: Weller RO (ed) Nervous system, muscle and eyes. Systemic Pathology, 3rd edn, vol. 4, Churchill Livingstone, Edinburgh, pp 3–35Google Scholar
- Lantos PL (1990b) Histological and cytology reactions. In: Weller RO (ed) Nervous system, muscle and eyes. Systemic Pathology, 3rd edn, vol. 4, Churchill Livingstone, Edinburgh, pp 36–63Google Scholar
- Nauta WJH, Gygax PA (1954) Silver impregnation of degenerating axons in the central nervous system. A modified technic: Stain Technol 29:91–93Google Scholar
- Rogers-Johnson P, Gajdusek DC, Morgan OSEC et al. (1985) HTLV1 and HTLV111 antibodies and tropical spastic paraparisis. Lancet ii:1248–1249Google Scholar
- Russell DS, Rubinstein LJ (1989) Effects of radiation and other forms of energy on intracranial and intraspinal tumours and their surrounding tissues. In: Pathology of tumours of the nervous system, 5th edn. Edward Arnold, London, pp 871–879Google Scholar
- Weller RO (1985) Pathology of multiple sclerosis. In: Mathews WB, Acheson ED, Batchelor JR, Weller RO (eds) McAlpine’s multiple sclerosis. Churchill Livingstone, Edinburgh, pp 301–343Google Scholar
- Williams B (1992) Syringomyelia. In: Findlay G, Owen R (eds) Surgery of the spine, vol 2. Blackwell Scientific Publications, Oxford, pp 891–906.Google Scholar