Photodynamic Therapy in Dermatology

  • Sean W. Lanigan


Photodynamic therapy (PDT) involves the therapeutic combination of a photosensitiser administered to the patient and its activation by light. This combination generates the formation of highly reactive oxygen intermediates which cause irreversible tissue injury and necrosis. Oxygen must be present in the tissue to effect damage. Van Tappeiner used this combination with eosin as the photosensitiser and artificial light for the treatment of skin carcinomas as early as 1903 but it was not until the 1970s that PDT became more widely investigated.


Photodynamic Therapy Basal Cell Carcinoma Complete Response Rate Mycosis Fungoides Port Wine Stain 
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References and Further Reading

Systemic Photodynamic Therapy

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Topical Photodynamic Therapy for Cutaneous Malignancies

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Photodynamic Therapy for Benign Skin Disease

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Copyright information

© Springer-Verlag London 2000

Authors and Affiliations

  • Sean W. Lanigan
    • 1
  1. 1.Department of DermatologyPrincess of Wales HospitalBridgendUK

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