Hydrogels for Ocular Posterior Segment Drug Delivery
This chapter discusses emerging hydrogel technology for drug delivery to the back of the eye to treat retinal diseases. The review includes design, characterization and optimization of hydrogels, and advantages and disadvantages of intravitreally and subconjunctivally administrated hydrogels for retinal therapy. Future direction of hydrogel technology for targeted and sustained delivery of drugs to the retina for individualized medicine is also laid out.
KeywordsDiabetic Macular Edema Retinal Vein Occlusion PLGA Microsphere Retinal Pigment Epithelium Drug Release Kinetic
The work was supported by the NIH, JDRF and Coulter Foundation grants. TWG is the Jack and Nancy Turner Professor.
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