Abstract
One of the major concerns for both short- and long-duration spaceflight is the phenomenon of cardio-vascular deconditioning. Exercise deconditioning during spaceflight may significantly affect a crewmember’s ability to perform strenuous or prolonged tasks during and after a spaceflight mission, respond to an emergency situation, or assist a crewmate who might be incapacitated. This chapter introduces the principles of cardio-vascular fluid and electrolyte control to shed light on the symptoms typically reported by astronauts during and after spaceflight. Data from flight experiments are discussed, as well as the value of ground-based models such as bed rest studies. The value of exercise, inflatable suits, saline loading, and artificial gravity is also discussed (Figure 4.1)
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Notes
- 1.
Earth’s gravity may determine the location and size of internal organs such as the heart. For example, Lillywhite et al. [1997] noticed that the heart of the tree snake, that is crawling up and down trees and therefore must cope with gravity, was closer to the brain than the land or sea snakes, who spend most of their life in a horizontal position or are neutrally buoyant. The tree snake was the most tolerant to centrifugation, suggesting that it would be more gravity tolerant than the other snakes as it did not have to carry blood over as great a distance from the heart to the brain [Morey-Holton, 1999].
- 2.
The authors of a Russian report [Popov et al., 2004] referred to the initial phase of flight as a “dead period” during which the decrease in physical condition is so severe that none of the countermeasure regimes are sufficiently effective.
- 3.
During the ISS Expedition-6 crew return in May 2003, the Soyuz headed down at a steeper angle, thus decelerating faster than planned. As a result, the crew was subjected to 8–10 g for several minutes.
- 4.
It is interesting to note that research literature overwhelmingly shows the greatest benefits in markers of cardio-respiratory fitness are realized with higher intensity (85–100%), lower duration exercise protocols such as intermittent or interval programs combining short sprints with short to medium rest periods for a wide variety of populations ranging from heart disease patients to endurance athletes [Midgley and McNaughton, 2006].
References
Barratt M, Pool S (eds) (2008) Principles of Clinical Medicine for Space Flight. New York, NY: Springer
Buckey JC, Lane LD Jr, Levine BD, Watenpaugh DE, Wright SJ, Moore WE, Gaffney FA, Blomqvist CG (1996a) Orthostatic intolerance after spaceflight. Journal of Applied Physiology 81: 7–18
Buckey JC, Gaffney FA, Lane LD Jr, Levine BD, Watenpaugh DE, Wright SJ, Yancy CM Jr, Meyer DM, Blomqvist CG (1996b) Central venous pressure in space. Journal of Applied Physiology 81: 19–25
Charles JB, Bungo MW, Fortner GW (1994) Cardiopulmonary function. In: Space Physiology and Medicine. Nicogossian AE, Huntoon CL, Pool SL (eds) Philadelphia, PA: Lea & Febiger, Chapter 14
Churchill SE (1999) Response of cardiovascular system to spaceflight. In: Keys to Space. Houston A, Rycroft M (eds) Boston MA, McGraw Hill, Chapter 18.4, pp 1830–1834
Churchill SE, Bungo MW (1997) Response of the cardiovascular system to spaceflight. In: Fundamentals of Space Life Sciences. Churchill SE (ed) Malabar FL, Krieger Publishing Company, Volume I, Chapter 4
Eckberg DL, Fritsch JM (1992) Influence of 10-day head-down bedrest on human carotid baroreceptor-cardiac reflex function. Acta Physioogica Scandinavia 604: 69–76
Elert G (2002) Frames of Reference. The Physics Hypertextbook [online]. Available: http://hypertextbook.com/physics/mechanics/ [Accessed 9 October 2010]
English KE, Loehr JA, Laughlin MA, et al. (2008) Reliability of strength testing using the advanced resistive exercise device and free weights. Washington, DC: National Aeronautics and Space Administration, NASA Technical Paper, NAS/TP-2008-214782
Foldager N, Andersen TA, Jessen FB, Ellegaard P, Stadeager C, Videbaek R, Norsk P (1996) Central venous pressure in humans during microgravity. Journal of Applied Physiology 81: 408–412
Fritsch-Yelle JM, Charles JB, Jones MM, Beightol LA, Eckberg DL (1994) Spaceflight alters autonomic regulation of arterial pressure in humans. Journal of Applied Physiology 77: 1776–1783
Fritsch-Yelle JM, Whitson PA, Bondar RL, (1996) Subnormal norepinephrine release relates to presyncope in astronauts after spaceflight. Journal of Applied Physiology 81: 2134–2141
Fritsch-Yelle JM, Leuenberger UA, D’Aunno DS, et al. (1998) An episode of ventricular tachycardia during long-duration spaceflight. American Journal of Cardiology 81: 1391–1392
Gernhardt ML, Jones JA, Scheuring RA, et al. (2008) Risk of compromised EVA performance and crew health due to inadequate EVA suit systems. In: NASA’s Human Research Program Evidence Book. Chapter 8. Available at: http://humanresearch.jsc.nasa.gov/elements/smo/hrp_evidence_book.asp [Accessed 10 October 2010]
Gharib C, Custaud MA (2002) Orthostatic tolerance after spaceflight or simulated weightlessness by head-down bed-rest. Bulletin Academy National of Medicine 186: 733–746
Hamilton D (2008) Cardiovascular disorders. In: Principles of Clinical Medicine for Spaceflight. Barratt M, Pool SL (eds) Chapter 16, pp 317–360
Harm DL, Jennings RT, Meck JV, et al. (2001) Gender issues related to spaceflight: A NASA perspective. Journal of Applied Physiology 91: 2374–2383
Herault S, Fomina G, Alferova I, Kotovskaya A, Poliakov V, Arbeille P (2000) Cardiac, arterial and venous adaptation to weightlessness during 6-month MIR spaceflights with and without thigh cuffs (bracelets). European Journal of Applied Physiology 81: 384–390
Johnson RS, Dietlein LF (eds) (1977) Biomedical Results from Skylab. Washington, DC: National Aeronautics & Space Administration, Scientific & Technical Information Office, NASA SP-377
Kirsch KA, Rocker L, Gauer OH, Krause R, Leach C, Wicke HJ, Landry R (1984) Venous pressure in man during weightlessness. Science 225: 218–219
Levine B (1999) Human Cardio-Vascular Adaptation to Altered Environments. Transcript of a lecture given at the University of Texas Southwestern Medical Center
Levine B, Bungo M (2010) Cardiac atrophy and diastolic dysfunction during and after long duration spaceflight: Functional consequences for orthostatic intolerance, exercise capability and risk for cardiac arrhythmias [online] Available: http://www.nasa.gov/mission_pages/station/science/experiments/Integrated_Cardiovascular.html [Accessed 10 October 2010]
Lillywhite HB, Ballard RE, Hargens AR, Rosenberg HI (1997) Cardiovascular responses of snakes to hypergravity. Gravitational Space Biology Bulletin 10: 145–152
Linnarsson D (2001) Pulmonary function in space. In: A World Without Gravity. Seibert G (ed) Noordwijk: European Space Agency, ESA SP-1251, pp 48–57
Lujan BF, White RJ (1994) Human Physiology in Space. Teacher’s Manual. A Curriculum Supplement for Secondary Schools. Houston, TX: Universities Space Research Association
Martin DS, South DA, Garcia KM, Arbeille P (2003) Ultrasound in space. Ultrasound Medical Biology 29: 1–12
McDonald PV, Vanderploeg JM, Smart K, Hamilton D (2007) AST Commercial Human Space Flight Participant Biomedical Data Collection. Houston, TX: Wyle Laboratories, Technical Report LS-09-2006-001
Meck JV, Reyes CJ, Perez SA, Goldberger AL, Ziegler MG (2001) Marked exacerbation of orthostatic intolerance after long- vs. short-duration spaceflight in veteran astronauts. Psychosomatic Med 63: 865–873
Midgley AW, Mc Naughton LR (2006) Time at or near VO2max during continuous and intermittent running. A review with special reference to considerations for the optimisation of training protocols to elicit the longest time at or near VO2max. Journal of Sports Medicine Physiology & Fitness 46: 1–14
Moore TP, Thornton WE (1987) Space Shuttle in-flight and postflight fluid shifts measured by leg volume changes. Aviation, Space and Environmental Medicine 58: A91–A96
Moore AD, Lee SM, Stenger MB, Platts SH (2010) Cardiovascular exercise in the U.S. space program: Past, present and future. Acta Astronautica 66: 974–988
Morey-Holton ER (1999) Gravity, a weighty-topic. In: Rothschild L and Lister A (eds) Evolution on Planet Earth: The impact of the Physical Environment, New York: Academic Press
Norsk P (2001) Fluid and electrolyte regulation and blood components. In: A World Without Gravity. Seibert G (ed) Noordwijk: European Space Agency, ESA SP-1251, pp 58–68
Norsk P, Karemaker JM (2008) Counteracting hypertension with weightlessness? Looking Up – Europe’s Quiet Revolution in Microgravity Research. Scientific American Magazine, October 2008, pp 16–23. Available at: www.scientificamerican.com/media/pdf/ESAReader_LowRes.pdf [Accessed 10 October 2010]
Payne MW, Williams DR, Trudel G (2007) Space flight rehabilitation. American Journal of Physiology and Medical Rehabilitation 86: 583–591
Popov DV, Khusnutdinova DR, Shenkman BS, et al. (2004) Dynamics of physical performance during long-duration space flight (first results of “Countermeasure” experiment). Journal of Gravitational Physiology 11: 231–232
Rossum A, Ziegler M, Meck J (2001) Effect of spaceflight on cardio-vascular responses to upright posture in a 77-year-old astronaut. American Journal of Cardiology 88: 1335–1337
Sawin CF, Baker E, Black FO (1998) Medical investigations and resulting countermeasures in support of 16-day Space Shuttle missions. Journal of Gravitational Physiology 5: 1–12
Scheuring RA, Jones JA, Polk JD, et al. (2007) The Apollo Medical Operations Project: Recommendations to Improve Crew Health and Performance for Future Exploration Missions and Lunar Surface Operations. Washington, DC: National Aeronautics and Space Administration, NASA TM-2007-214755
Smet G, Nordheim T, Hammons E, Rosenberg M (2010) Analog Map to Mars: A path towards sustainable human space exploration. Paper presented at the IAC Conference, Prague, 26 September-1 October, IAC-10-D3.1.7
Watenpaugh DE, Hargens AR (1995) The cardiovascular system in microgravity. In: Handbook of Physiology. Fregly MJ, Blatteis CM (eds) New York: Oxford University Press, Volume 1, pp 631–734
West J (1968) Regional differences in the lung. Postgraduate Medicine Journal 44:120–122
West JB, Elliott AR, Guy HJB, Prisk GK (1997) Pulmonary function in space. Journal of the American Medical Association 277: 1957–1961
Yates BJ (1996) Vestibular influences on cardiovascular control. In: Vestibular-Autonomic Regulation. Yates BJ, Miller AD (eds) Boca Raton FL, CRC Press, pp 97–111
Zak A (2008) Soyuz Development History [online]. Available at URL: http://www.russianspaceweb.com/Soyuz_acrv.html [Accessed 10 October 2010]
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2011 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
Clément, G. (2011). The Cardio-Vascular System in Space. In: Fundamentals of Space Medicine. Space Technology Library, vol 23. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9905-4_4
Download citation
DOI: https://doi.org/10.1007/978-1-4419-9905-4_4
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4419-9904-7
Online ISBN: 978-1-4419-9905-4
eBook Packages: EngineeringEngineering (R0)