Pulmonary Vasculitis

  • Ulrich Specks
  • Karina A. Keogh


Pulmonary vasculitis is usually but one manifestation of a systemic autoimmune disease. Primary vasculitis syndromes commonly affecting the respiratory tract are Wegener’s granulomatosis (WG), microscopic polyangiitis (MPA), and the Churg–Strauss syndrome. They are small-vessel vasculitides characterized by the presence of antineutrophil cytoplasmic autoantibodies (ANCA). This chapter provides an overview for a diagnostic approach to these patients that enables disease severity-adapted therapy. The respiratory manifestations of other vasculitides including Takayasu’s arteritis, Behcet’s disease, and Goodpasture’s disease are also discussed.


Pulmonary vasculitis Wegener’s granulomatosis Microscopic polyangiitis Churg–Strauss syndrome Antineutrophil cytoplasmic autoantibodies 


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© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Division of Pulmonary and Critical Care MedicineMayo ClinicRochesterUSA

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