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Neuroprotection and Physical Preconditioning: Exercise, Hypothermia, and Hyperthermia

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Innate Tolerance in the CNS

Part of the book series: Springer Series in Translational Stroke Research ((SSTSR))

Abstract

Exercise, hypothermia, and hyperthermia are preconditioning methods that vastly differ in terms of the physical properties of their respective stimuli. Despite their differences, these varying physical stimuli provide different value in terms of potential clinical utility. This chapter reviews the features and mechanisms underlying the cerebral protection that is conferred through the utilization of exercise, hypothermia, and hyperthermia. The neuroprotection derived from these various treatment modalities underlies their use in clinical settings, and it provides necessary background information for potential therapeutic and pharmaceutical interventions in the future.

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Authors and Affiliations

  1. Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, MI, USA

    Ryan Kochanski, David Dornbos III & Yuchuan Ding

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  1. Ryan Kochanski
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  2. David Dornbos III
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  3. Yuchuan Ding
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Correspondence to Yuchuan Ding .

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Editors and Affiliations

  1. , Departments of Neurosurgery, Washington University School of Medicine, South Kingshighway Boulevard, St. Louis, 63110, Missouri, USA

    Jeffrey M. Gidday

  2. , Department of Neurology, University of Miami Miller School of Med, Miami, 33136, Florida, USA

    Miguel A. Perez-Pinzon

  3. Loma Linda University, 11234 Anderson Street, Room 2562B, Loma Linda, 92354, California, USA

    John H. Zhang

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Kochanski, R., Dornbos, D., Ding, Y. (2013). Neuroprotection and Physical Preconditioning: Exercise, Hypothermia, and Hyperthermia. In: Gidday, J., Perez-Pinzon, M., Zhang, J. (eds) Innate Tolerance in the CNS. Springer Series in Translational Stroke Research. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9695-4_5

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  • DOI: https://doi.org/10.1007/978-1-4419-9695-4_5

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