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Sample Preparation for Select Nonsolid Dosage Forms

  • Xin Bu
  • Sachin Chandran
  • John Spirig
  • Qinggang Wang
Chapter

Abstract

Solid oral doses intended for the patient to swallow are the most common form of drug delivery, but formulations for other mechanisms of delivery exist to support patient needs. The state of the patient (e.g., inability to swallow), abilities of the patient to reliably self-dose (e.g., pediatric population, geriatric population), or even the physical properties of the drug (e.g., biologics) often require a nonsolid oral formulation. This chapter reviews sample preparation methods of dosage forms classified as oral liquids, semi-solids, nonoral solids, and parenterals. Products that fall into these classes include oral suspensions, syrups, oral solutions, creams, ointments, gels, topical powders, suppositories, transdermal systems, and injectables.

Keywords

Oral Solution Oral Suspension Ointment Sample Clindamycin Phosphate Erythromycin Estolate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Xin Bu
    • 1
  • Sachin Chandran
    • 2
  • John Spirig
    • 3
  • Qinggang Wang
    • 3
  1. 1.Analytical Research and DevelopmentBristol-Myers Squibb CompanyNew BrunswickUSA
  2. 2.BiopharmaceuticsBristol-Myers Squibb CompanyNew BrunswickUSA
  3. 3.Analytical Research and DevelopmentBristol-Myers Squibb CompanyNew BrunswickUSA

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