Heraclenol and Isopimpinellin: Two Rare Furocoumarins from Ruta montana

Abstract

Ruta montana,is a common specie of the genusRuta,(Rutaceae) but still studied since very recently four new alkaloids have been isolated from this specie’.The presence of xanthotoxin, bergapten and other known furocoumarins have been reported fromRuta montana,^2-5but isopimpinellin²and heraclenol³are two rare furocoumarins reported here for the first time from the specie and the genusRuta,respectively. Few plants contain heraclenol and isopimpinellin. recent pharmacological studies on isopimpinellin have shown it’s antimicrobial activity⁶heraclenol have been reported for it’s anti-inflammatory⁷ and anti-mycobacterial⁸properties with helpful nmr high techniques, we succeeded to identify heraclenol and isopimpinellin, two furocoumarins isolated for the first time fromRutamontana.,