Biodiversity pp 261-264 | Cite as

Antioxidant Activity of Capsicum annuum L. Fruit Extracts on Acetaminophen Toxicity

  • Bilgen Eryilmaz
  • Göknur Aktay
  • Funda Bingöl


Parasetamol is very safe drug when used in therapeutic doses, it is known to cause lipid peroxidation and hepatotoxicity after overdose 1,2. Its toxicity has been attributed to the cytochrome P-450 catalyzed formation of a highyl reactive metabolic species, the N-acetyl-p-benzoqoinone imine, which is thought to bind covalently to protein in vivo. Paracetamol-induced lipid peroxidation (LPO) was inhibited by antioxidants such as vitamin E and vitamin C1.


Lipid Peroxidation Antioxidant Activity Fruit Extract Chilli Pepper Control Group Animal 
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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Bilgen Eryilmaz
    • 1
  • Göknur Aktay
    • 2
  • Funda Bingöl
    • 1
  1. 1.Department of PharmacognosyGazi University, Faculty of PharmacyAnkaraTurkey
  2. 2.Institute of Forensic Medicine, Toxicology UnitAnkara UniversityAnkaraTurkey

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