Auditory Evoked Potentials
Since one of the earliest systematic observations of the physiologic effects of anaesthetic agents of John Snow in 1847 our interest of measures of the level of anaesthesia has persisted and a variety of approaches and technologies have meanwhile been introduced and utilized. Today, the practice of anaesthesia remains one of the safest and most effective in medicine. So why monitor the central nervous system (CNS)? Like all new technologies, CNS monitoring devices will certainly add something to the cost of delivering anaesthesia. On the other hand, there is no doubt that significant unpredictability and uncertainty still exists in the delivery of anaesthetic drugs. This is reflected in the variety of suggested dosing regimens, especially in intravenous anaesthesia. Some patients still suffer intra-operative awareness and may consecutively develop posttraumatic stress disorder,1 whereas others still have prolonged recovery due to relative overdosing even with otherwise short-acting drugs.
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- 4.E. W. Jensen, P. Lindholm, S. W. Henneberg, Autoregressive modeling with exogenous input of auditory evoked potentials to produce an online depth of anaesthesia index, Methods Inform. Med. 35, 256–260 (1996).Google Scholar
- 7.D. Schwender, I. Keller, S. Klasing, and C. Madler, Akustisch evozierte Potentiate mittlerer Latenz (AEPML) unter hochdosierter Opioidanalgesie, Anaesthesisi 39, 299–305 (1990).Google Scholar
- 10.H. Litvan, E. W. Jensen, M. Revuelta, S. W. Henneberg, P. Paniagua, J. M. Campos, P. Martinez, P. Caminal and J. M. V. Landeira, Comparison of auditory evoked potentials and the A-line ARX index for monitoring the hypnotic level during sevoflurane and propofol induction, Acta Anaesthesiol. Scand. 46, 245–251 (2002).PubMedCrossRefGoogle Scholar
- 24.V. Bonhomme, G. Plourde, P. Meuret, P. Fiset and S. Backman, Auditory steady-state response and bispectral index for assessing level of consciousness during propofol sedation and hypnosis, Anesth. Analg. 91,1398–1403(2000).Google Scholar
- 27.E. Kochs, CJ. Kalkman, C. Thornton, D. E. Newton, P. Bischoff, H. Kuppe, J. Abke, E. Konecny, W. Nahm and G. Stockmanns, Middle latency auditory evoked responses and electroencephalographic derived variables do not predict movement to noxious stimulation during 1 minimum alveolar anesthetic concentration isoflurane/nitrous oxide anesthesia, Anesth. Analg. 88,1412–1417 (1999).PubMedGoogle Scholar