Abstract
In parallel with increasing concern about the reproductive effects of endocrine disrupters in the environment, evidence has been accumulating that developmental exposure to estrogenic hormones can cause a variety of abnormalities on the male reproductive tract (reviewed by Nagao, 1999). However, little is still known about transgenerational toxicity of estrogens, except for the potential of a transgenerational carcinogenic effect of diethylstilbestrol (DES) reported in mice by (1984) and others. We carried out the present study as an attempt to fill this gap in our knowledge.
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Nagao, T., Kagawa, N., Nakagomi, M., Fujikawa, K. (2003). Increased Incidence of Malformations in the Offspring of Male Mice Prenatally Exposed to Synthetic Estrogens. In: Robaire, B., Hales, B.F. (eds) Advances in Male Mediated Developmental Toxicity. Advances in Experimental Medicine and Biology, vol 518. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9190-4_18
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DOI: https://doi.org/10.1007/978-1-4419-9190-4_18
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