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Clinical Aspects of Bone Metastases in Prostate Cancer

  • Shi-Ming Tu
  • Sue-Hwa Lin
Part of the Cancer Treatment and Research book series (CTAR, volume 118)

Abstract

Bone is the second most common site of metastases in human cancer. At least two-thirds of the approximately 553,400 Americans who die from cancer each year have bone metastases (Greenlee et al., 2001). Prostate, breast, and lung cancers account for at least 80% of the skeletal metastases. Tumors arising in the prostate and breast are particularly prone to disseminate to bone; up to 85% of patients with these cancers have evidence of bone metastases at autopsy. Carcinomas of the lung, thyroid, and kidney also commonly spread to the bone (30–40%). However, tumors of the gastrointestinal tract rarely metastasize to the bone (5%) (Galasko, 1986).

Keywords

Prostate Cancer Bone Metastasis Radical Prostatectomy Zoledronic Acid Metastatic Prostate Cancer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  • Shi-Ming Tu
    • 1
  • Sue-Hwa Lin
    • 1
    • 2
  1. 1.Department of Genitourinary Medical OncologyThe University of Texas, M.D. Anderson Cancer CenterHoustonUSA
  2. 2.Molecular PathologyThe University of Texas, M.D. Anderson Cancer CenterHoustonUSA

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