Pseudomonas pp 575-601 | Cite as

The Outer Membranes of Pseudomonads

  • Sandeep Tamber
  • Robert E. W. Hancock


The study of bacterial cell surfaces began in 1675 when Leeuwenhoek peering through his microscope wondered what “held [bacteria] together, or what contained them”92. Since that time, our knowledge of cell surfaces, namely the Gram-negative outer membrane, has grown considerably. In addition to containing the bacteria, the outer membrane mediates a myriad of functions including other structural roles such as maintaining bacterial shape and providing a scaffold for fimbriae and flagella. Another key function of the outer membrane is to mediate the interactions between Gram-negative bacteria and their environment, primarily by determining which compounds enter and exit the cell. This complex task involves the integration of lipidic components involved in the barrier function of the outer membrane and proteins involved in the uptake and efllux of the various compounds able to traverse this barrier.


Cystic Fibrosis Outer Membrane Pseudomonas Aeruginosa Outer Membrane Protein Pseudomonas Putida 
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Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  • Sandeep Tamber
    • 1
  • Robert E. W. Hancock
    • 1
  1. 1.Department of Microbiology and ImmunologyUniversity of British ColumbiaVancouverCanada

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