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Part of the book series: Proteases in Biology and Disease ((PBAD,volume 1))

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Abstract

Interstitial fibrosis of the lung is a final pathway of different lung disorders like idiopathic pulmonary fibrosis (IPF) or granulomatous lung diseases (for example sarcoidosis). Fibrotic areas were also found in patients suffering from chronic obstructive pulmonary disease (COPD). Acute lung injury (ALI) which can progress to acute respiratory distress syndrome (ARDS) can result in fibrotic tissue remodelling. Furthermore, during the course of asthma remodelling can lead to fibrosis as well.

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Wille, A., Welte, T., Bühling, F. (2003). Proteases in interstitial lung diseases. In: Lendeckel, U., Hooper, N.M. (eds) Proteases in Tissue Remodelling of Lung and Heart. Proteases in Biology and Disease, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9082-2_3

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